Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4365310 | 1.00 | LMNA (0.50) | LMNAKDM6BTSHRMEN1KMT2A | |
| SCHEMBL1857683 | 1.00 | LMNA (0.50) | LMNAKDM6BTSHRMEN1KMT2A | |
| SCHEMBL8953727 | 1.00 | LMNA (0.50) | LMNAKDM6BTSHRMEN1KMT2A | |
| SCHEMBL3091161 | 0.85 | TSHR (0.53) | LMNATSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL1666842 | 0.84 | MEN1 (0.52) | LMNATSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL19369766 | 0.84 | MAPK1 (0.50) | LMNATSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL4592273 | 0.84 | MAPK1 (0.50) | LMNATSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL8102675 | 0.84 | GSK3B (0.53) | LMNATSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL10436410 | 0.84 | CPA1 (0.57) | LMNATSHRMEN1KMT2ACYP2C19 | |
| SCHEMBL2561037 | 0.83 | TSHR (0.56) | LMNATSHRMEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1291417-B1 | NOVEL (R)-2-HYDROXY-3-PHENYLPROPIONATE (D-PHENYLLACTATE) DEHYDROGENASE AND GENE ENCODING THE SAME | MEIJI SEIKA KAISHA (JP) | 2007-02-21 | — | — | EP | claimed |
| CN-112384511-B | Endoparasite depsipeptides | 硕腾服务有限责任公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| CN-115851525-B | Chloramphenicol degrading bacterium, chloramphenicol dehydrogenase, encoding gene and application thereof | 安徽农业大学 | 2023-10-13 | — | — | CN | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| CN-111741956-B | Antiparasitic depsipeptides | 硕腾服务有限责任公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-116322683-A | Compounds as C5AR inhibitors | 科越医药(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116120240-A | FXIa inhibitor compound, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115851525-A | Chloramphenicol degrading bacteria, chloramphenicol dehydrogenase, encoding gene and application thereof | 安徽农业大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-114206854-B | FXIa inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-02-24 | — | — | CN | disclosed |
| EP-0736035-A1 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5541287-A | DIAGNOSIS USING CYCLIC TRIPEPTIDES WITH NITROBENZYL 1,4,7,10-TETRAAZACYCLODODECANE-N,N*,N**,N***TETRAACETIC ACID BIOTIN CONJUGATE FORMED BY ALKYLATION AND MULTISTAGE PROCESS | NEORX CORPORATION (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0718293-A1 | CYCLODEPSIPEPTIDE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995015335-A2 | PRETARGETING METHODS AND COMPOUNDS | NEORX CORPORATION (US) | 1995-06-08 | — | — | WO | disclosed |
| EP-0634408-A1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |
| CN-1080932-A | Depsipeptide derivative and manufacture method thereof and purposes | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-01-19 | — | — | CN | disclosed |
| US-5225431-A | Treatment of migraine | BURROUGHS WELLCOME CO. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0313397-B1 | THERAPEUTIC HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| CN-1035113-A | The heterogeneous ring compound that is used for the treatment of | WELLCOME FOUND (GB) | 1989-08-30 | — | — | CN | disclosed |
| EP-0313397-A1 | Therapeutic heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | LMNA 1682/4885KDM6B 4031/4885TSHR 1622/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | LMNA 2449/4885KDM6B 4186/4885TSHR 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.