Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287711 | 0.91 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL28912292 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL13985002 | 0.87 | HPGD (0.51) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL2089843 | 0.84 | POLB (0.56) | KDM4EALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL9977906 | 0.84 | ALDH1A1 (0.61) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL11659164 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL11437459 | 0.83 | KMT2A (0.64) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL3110441 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1KMT2ATSHRGAA | |
| SCHEMBL10817064 | 0.82 | SMN1; SMN2 (0.71) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL11767621 | 0.82 | KDM4E (0.70) | KDM4EALDH1A1KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063905-B1 | FUNGICIDAL N-PHENYLCARBAMATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-14 | — | — | EP | claimed |
| US-4482546-A | Fungicidal N-phenylcarbamates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-13 | — | — | US | claimed |
| EP-0063905-A1 | Fungicidal N-phenylcarbamates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-11-03 | — | — | EP | claimed |
| EP-0856001-B1 | PYRIMIDINE DERIVATIVES AS 5HT2C RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2002-08-28 | — | — | EP | disclosed |
| EP-0856001-A1 | PYRIMIDINE DERIVATIVES AS 5HT 2C?-RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-08-05 | — | — | EP | disclosed |
| US-5753663-A | 5HT2C ANTAGONIST, USEFUL FOR TREATING ANXIETY, PAIN, OBSESSIVE COMPULSIVE DISORDER, ALCOHOLISM, DEPRESSION, MIGRAINE, SLEEP DISORDER, ANOREXIA NERVOSA AND PRIAPISM | SYNTEX (U.S.A.) INC. (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1997012880-A1 | PYRIMIDINE DERIVATIVES AS 5HT2C-RECEPTOR ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 1997-04-10 | — | — | WO | disclosed |
| US-4690946-A | Fungicidal N-phenylcarbamates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-01 | — | — | US | disclosed |
| EP-0063905-B1 | FUNGICIDAL N-PHENYLCARBAMATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4482546-A | Fungicidal N-phenylcarbamates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-13 | — | — | US | disclosed |