Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.56 |
| ▸ | ADH1B | P00325 | 2/20 | 0.45 |
| ▸ | ADH1A | P07327 | 2/20 | 0.45 |
| ▸ | ADH7 | P40394 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744262 | 1.00 | TSHR (0.69) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL2639821 | 0.97 | TSHR (0.65) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL8850864 | 0.97 | TSHR (0.65) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL2905152 | 0.96 | CYP2C19 (0.62) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL1247661 | 0.96 | TSHR (0.73) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL1276412 | 0.96 | CYP2C19 (0.62) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL21686603 | 0.94 | TSHR (0.81) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL8011029 | 0.94 | TSHR (0.61) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL10704190 | 0.93 | CYP2C19 (0.59) | TSHRALDH1A1CYP2C19CYP1A2MEN1 | |
| SCHEMBL1781797 | 0.93 | TSHR (0.69) | TSHRALDH1A1CYP2C19CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-04-18 | — | — | US | claimed |
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | claimed |
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-04-18 | — | — | US | disclosed |
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-04-18 | — | — | US | disclosed |
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | SRM, SLC7A1, CATSPER1 | TSHR 732/4885ALDH1A1 1949/4885CYP2C19 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.