Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222733 | 0.83 | KEAP1 (0.57) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| Nitrogen SCHEMBL28658127 | 0.79 | KEAP1 (0.53) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24746192 | 0.78 | CFTR (0.43) | ALDH1A1KMT2AMEN1POLBCFTR | |
| SCHEMBL17774726 | 0.78 | KEAP1 (0.52) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21664323 | 0.77 | KDM4E (0.51) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24418014 | 0.77 | IDO1 (0.50) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL994342 | 0.76 | KDM4E (0.50) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3530679 | 0.76 | KEAP1 (0.50) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL406782 | 0.76 | KEAP1 (0.50) | KEAP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6018094 | 0.76 | KDM4E (0.50) | KEAP1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087842-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |