SCHEMBL222733

SCHEMBL222733

Nc1cc(F)c(F)cc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.57
IDO1 P14902 1/20 0.52
KDM4E B2RXH2 7/20 0.50
KMT2A Q03164 4/20 0.50
GFER P55789 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
TDP1 Q9NUW8 4/20 0.48
MAPT P10636 4/20 0.48
MEN1 O00255 3/20 0.48
THRB P10828 2/20 0.48
RECQL P46063 2/20 0.48
USP2 O75604 1/20 0.48
POLB P06746 1/20 0.48
PKM P14618 1/20 0.48
APEX1 P27695 1/20 0.48
BLM P54132 1/20 0.48
MCL1 Q07820 1/20 0.48
ALDH1A1 P00352 6/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL28658127 0.96 KEAP1 (0.53) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL17774726 0.85 KEAP1 (0.52) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL99199 0.84 KEAP1 (0.50) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL3530679 0.83 KEAP1 (0.50) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL937859 0.83 KEAP1 (0.50) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL406782 0.83 KEAP1 (0.50) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL994342 0.83 KDM4E (0.50) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL1096218 0.83 KEAP1 (0.50) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL7513745 0.83 KEAP1 (0.50) KEAP1IDO1KDM4EKMT2AGFER
SCHEMBL2726898 0.83 KDM4E (0.50) KEAP1IDO1KDM4EKMT2AGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 778 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
EP-3967714-B1 VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES SEKISUI CHEMICAL CO LTD (JP) 2026-01-07 EP claimed
CN-118561862-A Preparation of 10, 11-difluoro camptothecine derivative and application thereof in anti-tumor aspect 兰州大学 2024-08-30 CN claimed
US-20240011009-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2024-01-11 US claimed
US-20230349872-A1 GUN SHOT RESIDUE FIELD KIT VERITEQUE USA, INC. 2023-11-02 US claimed
CN-115010671-B One-step synthesis method of 2-substituted quinazolinone 江苏大学 2023-10-10 CN claimed
US-20230220589-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2023-07-13 US claimed
EP-4182657-A1 GUN SHOT RESIDUE FIELD KIT Veriteque USA, Inc. (US) 2023-05-24 EP claimed
CN-116113822-A Bullet residue field kit 韦里特克美国有限公司 2023-05-12 CN claimed
EP-4127157-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-02-08 EP claimed
EP-0385253-B1 PROCESS FOR PREPARING 2,4,5-TRIFLUOROBENZOIC ACID OCCIDENTAL CHEMICAL CORPORATION (US) 1993-09-29 EP claimed
EP-0417445-A1 Single pot process for making a fluoroanthranilic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1991-03-20 EP claimed
US-4994606-A Decarboxylating 4,5-difluorophthalic anhydride by heating in dimethyl acetamide; nitration, reduction OCCIDENTAL CHEMICAL CORPORATION (US) 1991-02-19 US claimed
EP-0385253-A1 Process for preparing 2,4,5-trifluorobenzoic acid OCCIDENTAL CHEMICAL CORPORATION (US) 1990-09-05 EP claimed
US-4954639-A REACTING FLUOROPHTHALIC ACID COMPOUND WITH HYDROXYLAMINE OR SALT OCCIDENTAL CHEMICAL CORPORATION (US) 1990-09-04 US claimed
US-4876387-A FORMING AMINE SALT OF 4,5-DIFLUOROANTHRANILIC ACID, DIAZOTIZATION, DECOMPOSITION OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-24 US claimed
US-4833270-A Process for preparing 2-chloro-4,5-difluorobenzoic acid AMERICAN CYANAMID COMPANY (US) 1989-05-23 US claimed
US-4521616-A Method for the preparation of fluoroanthranilic acids OCCIDENTAL CHEMICAL CORPORATION (US) 1985-06-04 US claimed
US-4343951-A Method for the preparation of fluoroaniline HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-08-10 US claimed
EP-0055629-A1 Process for preparing fluoroanthranilic compounds HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-07-07 EP claimed