Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12066211 | 0.84 | HCAR2 (0.48) | ALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL7519440 | 0.74 | TSHR (0.46) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL7503514 | 0.74 | TSHR (0.41) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL15023610 | 0.72 | TRPM2 (0.50) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL15023609 | 0.72 | TRPM2 (0.50) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL7509246 | 0.72 | TSHR (0.46) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL7503519 | 0.68 | TSHR (0.45) | ALDH1A1HSD17B10HPGDKDM4EDHODH | |
| SCHEMBL993102 | 0.68 | HPGD (0.65) | ALDH1A1HSD17B10HPGDKDM4EMAPK8 | |
| SCHEMBL4897624 | 0.67 | KDM6B (0.69) | ALDH1A1HSD17B10HPGDKDM4EKDM6B | |
| SCHEMBL466141 | 0.67 | PLK1 (0.63) | ALDH1A1HSD17B10HPGDKDM4EMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576540-A2 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011150156-A2 | HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2011-12-01 | — | — | WO | disclosed |