Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 3/20 | 0.69 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CDK2 | P24941 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | THPO | P40225 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13199682 | 0.95 | KDM6B (0.70) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| SCHEMBL11499132 | 0.94 | KDM6B (0.68) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| Enfenamic Acid SCHEMBL25191 | 0.90 | KDM6B (0.68) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| Enfenamic Acid SCHEMBL10935569 | 0.88 | KDM6B (0.66) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| SCHEMBL28326146 | 0.86 | NPC1 (0.54) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| SCHEMBL9838103 | 0.84 | KDM4E (0.66) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| SCHEMBL8689214 | 0.84 | ALDH1A1 (0.79) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| SCHEMBL1665592 | 0.83 | ALDH1A1 (0.67) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| SCHEMBL3514128 | 0.82 | KDM6B (0.59) | KDM6BKDM4CALDH1A1HSD17B10HPGD | |
| SCHEMBL993102 | 0.81 | HPGD (0.65) | KDM6BKDM4CALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715146-A | Eradicate the method and composition of leukaemia cell | 哈佛学院校长同事会 | 2019-05-03 | — | — | CN | disclosed |
| US-20080103205-A1 | Pesticidal compositions and methods of use | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. | 2008-05-01 | — | — | US | disclosed |
| WO-2007050867-A2 | PESTICIDAL COMPOSITIONS AND METHODS OF USE | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| WO-1999002190-A1 | ORGAN-SPECIFIC TARGETING OF CATIONIC AMPHIPHILE/RETINOBLASTOMA ENCODING DNA COMPLEXES FOR GENE THERAPY | GENZYME CORPORATION (US) | 1999-01-21 | — | — | WO | disclosed |
| US-4994493-A | Treatment of cerebral edema | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN (DE) | 1991-02-19 | — | — | US | disclosed |
| EP-0210574-A2 | N-substituted 5-nitro anthranilic acids, process for their preparation, their use and pharmaceutical compositions based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-02-04 | — | — | EP | disclosed |
| US-4350822-A | Antilipidemicpara-[aryl(alkyl or alkenyl)amino]benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| US-4185115-A | Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103205-A1 | Pesticidal compositions and methods of use | SLC47A1, SLC22A8, SLC47A2 | KDM6B 2982/4885KDM4C 2607/4885ALDH1A1 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.