Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL18005921 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL30031849 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15482357 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL17868581 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL4051182 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8359062 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL455731 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL9465334 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6135726 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL28139628 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8740 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122074590-A | Preparation method of sheep Zhuang powder | — | 2026-05-26 | — | — | CN | claimed |
| CN-121426466-B | Concrete anti-cracking admixture for highland alpine regions and preparation method and application thereof | 中铁京诚工程检测有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122059750-A | Preparation process of organic high molecular carbon composite loss control fertilizer | 中农金瑞肥业有限公司 | 2026-05-19 | — | — | CN | claimed |
| EP-4741361-A1 | COMPOSITE AND METHOD OF ITS PRODUCTION | Chomicka, Marta (PL) | 2026-05-13 | — | — | EP | claimed |
| EP-4739733-A1 | COMPOSITIONS FOR FACILITATING SELECTIVELY FILTERING OF INCIDENT LIGHT | Iyris Technology Limited (GB) | 2026-05-13 | — | — | EP | claimed |
| CN-121623961-B | Copper oxide mineral flotation inhibitor and flotation method of copper oxide or copper cobalt oxide ore | 中南大学 | 2026-05-12 | — | — | CN | claimed |
| CN-122017204-A | Tracing method for geothermal liquid activity of sedimentation basin | 南京大学 | 2026-05-12 | — | — | CN | claimed |
| EP-3580271-B1 | FLAME RETARDANT-STABILIZER COMBINATION FOR THERMOPLASTIC POLYMERS | CLARIANT INT LTD (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4729053-A1 | SOLID DISPERSION OF P2X4 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Wuhan Createrna Science and Technology Co.,Ltd. (CN) | 2026-04-22 | — | — | EP | claimed |
| US-20260103589-A1 | THERMOPLASTIC POLYOLEFIN COMPOSITIONS | Kraton Corporation (US) | 2026-04-16 | — | — | US | claimed |
| EP-0077966-A1 | Process for the preparation of setting resin compositions | SIEMENS AKTIENGESELLSCHAFT (DE) | 1983-05-04 | — | — | EP | claimed |
| US-4353751-A | REACTION OF ALUMINUM HYDROXIDE, CALCIUM CARBONATE, AND CALCIUM HYDROXIDE IN PRESENCE OF WATER | LAFARGE (FR) | 1982-10-12 | — | — | US | claimed |
| EP-0048449-A1 | Method of purifying gases from acid gas components, especially purifying flue gases from sulphur dioxide | Fläkt Aktiebolag (SE) | 1982-03-31 | — | — | EP | claimed |
| US-4185080-A | Method of reducing the sulfur oxide content of combustion gases resulting from combustion of sulfur-containing fossil fuels | Rohrbach, Rudolf (DE) | 1980-01-22 | — | — | US | claimed |
| US-4108764-A | Method and apparatus for removing gas from interior of hollow-fiber permeability apparatus | NIPPON CEON CO., LTD. (JA) | 1978-08-22 | — | — | US | claimed |
| US-4076922-A | COORDINATION POLYMERIZATION CATALYST | CHISSO CORPORATION (JA) | 1978-02-28 | — | — | US | claimed |
| US-4039492-A | Synthetic fiber water base surface coating composition | HAMILTON MATERIALS (US) | 1977-08-02 | — | — | US | claimed |
| US-4011299-A | CALCIUM AND MAGNESIUM OXIDE, REDUCING GASES, FORMING 2A SULFIDES | MONSANTO COMPANY (US) | 1977-03-08 | — | — | US | claimed |
| US-3996179-A | Printing inks for transfer printing | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | claimed |
| US-3969206-A | Process for stabilization of ultraviolet light curable unsaturated polyester resin mixture | AKZONA INCORPORATED (US) | 1976-07-13 | — | — | US | claimed |