Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL75144 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL30031849 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL18005921 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL175616 | 0.94 | — | — | |
| Bicarbonate SCHEMBL9618146 | 0.94 | — | — | |
| Bicarbonate SCHEMBL25251920 | 0.94 | — | — | |
| Bicarbonate SCHEMBL3037570 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1160585 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5680462 | 0.94 | — | — | |
| Bicarbonate SCHEMBL17746828 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260103589-A1 | THERMOPLASTIC POLYOLEFIN COMPOSITIONS | Kraton Corporation (US) | 2026-04-16 | — | — | US | claimed |
| EP-4725991-A1 | THERMOPLASTIC POLYOLEFIN COMPOSITIONS | Kraton Polymers Nederland B.V. (NL) | 2026-04-15 | — | — | EP | claimed |
| EP-4153669-B1 | HIGHLY FILLED AND FLEXIBLE POLYOLEFIN COMPOSITION | BASELL POLIOLEFINE ITALIA SRL (IT) | 2024-11-06 | — | — | EP | claimed |
| CN-115516017-B | Highly filled and flexible polyolefin compositions | 巴塞尔聚烯烃意大利有限公司 | 2023-09-26 | — | — | CN | claimed |
| US-20230183462-A1 | HIGHLY FILLED AND FLEXIBLE POLYOLEFIN COMPOSITION | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2023-06-15 | — | — | US | claimed |
| EP-4153669-A1 | HIGHLY FILLED AND FLEXIBLE POLYOLEFIN COMPOSITION | Basell Poliolefine Italia S.r.l. (IT) | 2023-03-29 | — | — | EP | claimed |
| CN-115516017-A | Highly filled and flexible polyolefin compositions | 巴塞尔聚烯烃意大利有限公司 | 2022-12-23 | — | — | CN | claimed |
| EP-3383815-B1 | FLAME-RETARDANT OPTICAL FIBER COATING | CORNING INC (US) | 2022-04-27 | — | — | EP | claimed |
| WO-2021233875-A1 | HIGHLY FILLED AND FLEXIBLE POLYOLEFIN COMPOSITION | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2021-11-25 | — | — | WO | claimed |
| US-10222547-B2 | Flame-retardant optical fiber coating | CORNING INCORPORATED (US) | 2019-03-05 | — | — | US | claimed |
| US-5032321-A | Ethylene copolymers | NORSOLOR (ORKEM GROUP) (FR) | 1991-07-16 | — | — | US | claimed |
| US-5021484-A | Self-extinguishing mixtures with an inorganic or organic salt; materials handling | GURIT-ESSEX AG (CH) | 1991-06-04 | — | — | US | claimed |
| WO-1991007473-A1 | SEALANT | AIRSEAL PTY LIMITED (AU) | 1991-05-30 | — | — | WO | claimed |
| WO-1991004291-A1 | COMPOSITIONS COMPRISING A PHENOLIC RESIN AND CEMENT | CROMPTON DESIGN MANUFACTURING LIMITED (GB) | 1991-04-04 | — | — | WO | claimed |
| EP-0420302-A1 | Fire-retardant additives and their uses | BRUNNER MOND & COMPANY LIMITED (GB) | 1991-04-03 | — | — | EP | claimed |
| CN-1039602-A | After solidifying, become resin batch mixing of nonflammable and high-temperature polymer resin and preparation method thereof | GURIT ESSEX AG (CH) | 1990-02-14 | — | — | CN | claimed |
| EP-0349320-A2 | Flame retarding compositions | CROMPTON DESIGN MANUFACTURING LIMITED (GB) | 1990-01-03 | — | — | EP | claimed |
| US-4879066-A | Fire retardant additives and their uses | CEEPREE PRODUCTS LIMITED (GB) | 1989-11-07 | — | — | US | claimed |
| EP-0322135-A1 | Materials for and manufacture of fire and heat resistant components | CROMPTON DESIGN MANUFACTURING LIMITED (GB) | 1989-06-28 | — | — | EP | claimed |
| EP-0195982-A2 | System and use thereof for collecting chemical-physical, electrochemical and mechanical parameters for designing and/or operating cathodic protection plants | ORONZIO DE NORA S.A. (CH) | 1986-10-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103589-A1 | THERMOPLASTIC POLYOLEFIN COMPOSITIONS | PGM2, B2M, VCL | CA4 4337/4885CA1 3614/4885FAHD1 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.