⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256382 | 0.86 | TSHR (0.41) | — | |
| SCHEMBL4446962 | 0.83 | SLC6A3 (0.39) | — | |
| SCHEMBL18084896 | 0.83 | GPR84 (0.44) | — | |
| SCHEMBL688756 | 0.83 | GPR84 (0.44) | — | |
| SCHEMBL29958079 | 0.81 | — | — | |
| SCHEMBL29957730 | 0.81 | — | — | |
| SCHEMBL16281541 | 0.81 | — | — | |
| SCHEMBL18606076 | 0.81 | — | — | |
| SCHEMBL323329 | 0.81 | — | — | |
| SCHEMBL8011567 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631982-A2 | Silica based aggregates, elastomers reinforced therewith and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-01-04 | — | — | EP | claimed |
| EP-0631982-B1 | Silica based aggregates, elastomers reinforced therewith and tire with tread thereof | GOODYEAR TIRE & RUBBER (US) | 2002-01-09 | — | — | EP | disclosed |
| US-6068694-A | Silica based aggregates, elastomers reinforced therewith and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-05-30 | — | — | US | disclosed |
| US-5723529-A | Silica based aggregates, elastomers reinforced therewith and tire tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0631982-A2 | Silica based aggregates, elastomers reinforced therewith and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-01-04 | — | — | EP | disclosed |