Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GNG2 | P59768 | 1/20 | 0.47 |
| ▸ | GNB1 | P62873 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20476791 | 0.99 | PRMT1 (0.59) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| SCHEMBL5358935 | 0.87 | PRMT1 (0.80) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| SCHEMBL499135 | 0.84 | MAPT (0.64) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| SCHEMBL30599806 | 0.84 | MAPT (0.64) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| SCHEMBL5352933 | 0.81 | PRMT1 (0.62) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| SCHEMBL11230115 | 0.77 | PRMT1 (0.82) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| Eosin SCHEMBL113395 | 0.76 | PRMT1 (1.00) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| Eosin SCHEMBL29350830 | 0.76 | PRMT1 (1.00) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| Eosin SCHEMBL29381252 | 0.76 | PRMT1 (1.00) | PRMT1AKR1C1HSP90AA1MAPTMEN1 | |
| SCHEMBL5353279 | 0.75 | PRMT1 (0.78) | PRMT1AKR1C1HSP90AA1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001023526-A9 | ENGINEERED RADIATION RESISTANT BIOREMEDIATING BACTERIA | HENRY M JACKSON FOUNDATION (US) | 2002-10-03 | — | — | WO | disclosed |
| WO-2001023526-A1 | ENGINEERED RADIATION RESISTANT BIOREMEDIATING BACTERIA | THE HENRY M. JACKSON FOUNDATION (US) | 2001-04-05 | — | — | WO | disclosed |