Eosin

Eosin

SCHEMBL113395

O=C1OC2(c3ccccc31)c1cc(Br)c(O)c(Br)c1Oc1c2cc(Br)c(O)c1Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 1.00
AKR1C1 Q04828 1/20 0.64
TDP1 Q9NUW8 5/20 0.61
MEN1 O00255 5/20 0.61
KMT2A Q03164 5/20 0.61
RECQL P46063 3/20 0.61
THRB P10828 2/20 0.61
BLM P54132 2/20 0.61
ACE2 Q9BYF1 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
USP2 O75604 2/20 0.61
CDK2 P24941 1/20 0.61
CHAT P28329 1/20 0.61
BLVRB P30043 1/20 0.61
RXFP1 Q9HBX9 1/20 0.61
HSP90AA1 P07900 2/20 0.60
GNG2 P59768 1/20 0.59
GNB1 P62873 1/20 0.59
CYP3A4 P08684 3/20 0.57
ALDH1A1 P00352 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eosin SCHEMBL29350830 1.00 PRMT1 (1.00) PRMT1AKR1C1TDP1MEN1KMT2A
Eosin SCHEMBL29381252 1.00 PRMT1 (1.00) PRMT1AKR1C1TDP1MEN1KMT2A
Eosin SCHEMBL1436014 0.99 PRMT1 (0.97) PRMT1AKR1C1TDP1MEN1KMT2A
Eosin SCHEMBL461913 0.99 PRMT1 (0.97) PRMT1AKR1C1TDP1MEN1KMT2A
Eosin SCHEMBL16862387 0.99 PRMT1 (0.97) PRMT1AKR1C1TDP1MEN1KMT2A
SCHEMBL25027302 0.93 PRMT1 (0.86) PRMT1AKR1C1TDP1MEN1KMT2A
SCHEMBL18932171 0.93 PRMT1 (0.86) PRMT1AKR1C1TDP1MEN1KMT2A
SCHEMBL5356623 0.93 PRMT1 (0.86) PRMT1AKR1C1TDP1MEN1KMT2A
SCHEMBL11230115 0.90 PRMT1 (0.82) PRMT1AKR1C1TDP1MEN1KMT2A
SCHEMBL5358935 0.89 PRMT1 (0.80) PRMT1AKR1C1TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023192788-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE L'OREAL (FR) 2023-10-05 WO claimed
US-20230310285-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE L'OREAL (FR) 2023-10-05 US claimed
CN-116355437-A Preparation method for improving saturation of bromofluorescein lake 湖南金桥新材料科技有限公司 2023-06-30 CN claimed
EP-3636600-A1 A SORPTION COMPOSITION FOR COMPLEX WATER PURIFICATION EWI bvba (BE) 2020-04-15 EP claimed
EP-3080588-B1 METHOD FOR DETECTING CURING OF THE BINDER IN A MINERAL FIBRE PRODUCT ROCKWOOL INT (DK) 2018-09-05 EP claimed
WO-2018117964-A1 COLOURANT-INCORPORATED SILK FOR VALUE-ADDED COSMETICS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-06-28 WO claimed
US-7842826-B2 Process for synthesizing halogenated derivatives of fluorescein for use in the production of non-volatile memory devices STMICROELECTRONICS S.R.L. (IT) 2010-11-30 US claimed
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES STMICROELECTRONICS S.R.L. (IT) 2008-03-13 US claimed
US-6966213-B2 Rapid method for detecting leaks of hydraulic fluids in production plants NALCO COMPANY (US) 2005-11-22 US claimed
US-20050160795-A1 Rapid method for detecting leaks of hydraulic fluids in production plants ECOLAB USA INC. 2005-07-28 US claimed
US-20030108488-A1 Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants PROCTER & GAMBLE COMPANY, THE 2003-06-12 US claimed
EP-0305115-B1 IMPROVEMENTS IN OR RELATING TO RADIATION SENSITIVE COMPOUNDS E.I. du Pont de Nemours and Company (US) 1992-03-18 EP claimed
US-4933452-A Radiation sensitive isocyanurate compounds AGFA-GEVAERT. N.V. (BE) 1990-06-12 US claimed
EP-0305115-A2 Improvements in or relating to radiation sensitive compounds E.I. du Pont de Nemours and Company (US) 1989-03-01 EP claimed
US-4400249-A Partial synthesis process for preparing (+) -vincamine and related indolic alkaloids LINNEA S.A. (CH) 1983-08-23 US claimed
US-20260043720-A1 STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT VENTANA MED SYST INC (US) 2026-02-12 US disclosed
US-12496344-B2 Biophotonic materials and uses thereof FLE INT S R L (IT) 2025-12-16 US disclosed
US-4256727-A DYNAMIC IMAGES OF THE LIVER AND BILE DUCTS THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1981-03-17 US disclosed
US-4213904-A Fluorescent labeling reagents containing the fluorescein and eosin chromophores HAUGLAND RICHARD P 1980-07-22 US disclosed
US-4152411-A POLYPEPTIDE COUPLED WITH MARKER MATERIAL FOR IMMUNOASSAY AKZONA INCORPORATED (US) 1979-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080061289-A1 PROCESS FOR SYNTHESIZING HALOGENATED DERIVATIVES OF FLUORESCEIN FOR USE IN THE PRODUCTION OF NON-VOLATILE MEMORY DEVICES FASTKD5, KCNA5, KCNQ5 PRMT1 3963/4885AKR1C1 3130/4885TDP1 2574/4885
US-20030108488-A1 Compositions and methods to inhibit tartar and microbes using denture adhesive compositions with colorants TAS2R10, TAS1R1, TAS2R40 PRMT1 3444/4885AKR1C1 1058/4885TDP1 2193/4885
US-20260043720-A1 STABILIZED TWO-PART HEMATOXYLIN SOLUTION UTILIZING pH ADJUSTMENT SMCHD1, KIT, CD68 PRMT1 4537/4885AKR1C1 4162/4885TDP1 3572/4885
US-20230310285-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE TYR, CYB5R3, POLR1C PRMT1 324/4885AKR1C1 244/4885TDP1 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.