SCHEMBL5352933

SCHEMBL5352933

O=C1OC2(c3cc(Br)c(O)cc3Oc3c2ccc(O)c3Br)c2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 2/20 0.62
GNG2 P59768 1/20 0.57
GNB1 P62873 1/20 0.57
MAPT P10636 6/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
TDP1 Q9NUW8 4/20 0.54
FTO Q9C0B1 3/20 0.54
HTT P42858 2/20 0.54
RECQL P46063 2/20 0.54
BLM P54132 2/20 0.54
ACE2 Q9BYF1 2/20 0.54
CYP2C19 P33261 2/20 0.54
HPGD P15428 1/20 0.54
SMAD3 P84022 1/20 0.54
AKR1C1 Q04828 1/20 0.49
OPRM1 P35372 1/20 0.47
OPRD1 P41143 1/20 0.47
HSP90AA1 P07900 1/20 0.46
LMNA P02545 5/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5358935 0.89 PRMT1 (0.80) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL30599806 0.88 MAPT (0.64) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL499135 0.88 MAPT (0.64) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL29756279 0.87 FTO (0.73) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL5359408 0.87 FTO (0.73) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL29374142 0.87 GNG2 (0.74) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL328742 0.87 GNG2 (0.74) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL6269753 0.85 GNG2 (0.72) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL5356623 0.85 PRMT1 (0.86) PRMT1GNG2GNB1MAPTMEN1
SCHEMBL7514702 0.81 PRMT1 (0.60) PRMT1GNG2GNB1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7306632-B2 Leave-in color conditioner HAIRMARKER LLC (US) 2007-12-11 US disclosed
US-20050198746-A1 Leave-in color conditioner HAIRMARKER LLC 2005-09-15 US disclosed
US-5110723-A Assay for microorganisms; no surfactant necessary EASTMAN KODAK COMPANY (US) 1992-05-05 US disclosed
EP-0211898-B1 REDUCIBLE COMPOUNDS AND ANALYTICAL COMPOSITIONS, ELEMENTS AND ME THODS UTILIZING SAME EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-04-15 EP disclosed
EP-0190740-B1 USE OF SUBSTITUTED QUINONE ELECTRON TRANSFER AGENTS IN ANALYTICAL DETERMINATIONS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1991-11-27 EP disclosed
US-5045477-A Medical diagnosis EASTMAN KODAK COMPANY (US) 1991-09-03 US disclosed
US-5037762-A Determination Of Enzymes, Metabolites Or Living Cells With Quinone Derivatives EASTMAN KODAK COMPANY (US) 1991-08-06 US disclosed
US-4952495-A CLEAVING BLOCKED MOIETIES TO PRODUCE REDUCIBLE AND OXIDIZABLE COMPOUNDS; DETECTING HYDROLYTIC ENZYMES; QUINONE AND PHENAZINE COMPONENTS EASTMAN KODAK COMPANY (US) 1990-08-28 US disclosed
US-4912036-A Using a reducible dye; colorimetric analysis EASTMAN KODAK COMPANY (US) 1990-03-27 US disclosed
US-4888287-A PREFERENTIAL ACTION ON CYTOPLASMIC MEMBRANE EASTMAN KODAK COMPANY (US) 1989-12-19 US disclosed
US-4885240-A NITROGEN-CONTAINING BUFFERS; DETECTING ESCHERICHIA IN URINE; SOLUTION OR DRY ELEMENT EASTMAN KODAK COMPANY (US) 1989-12-05 US disclosed
US-4885239-A INHIBIT REDUCTION OF CHROMOGEN BY GRAMPOSITIVE BACTERIA EASTMAN KODAK COMPANY (US) 1989-12-05 US disclosed
US-4857271-A USING A QUINONE COMPOUND EASTMAN KODAK COMPANY (US) 1989-08-15 US disclosed
US-4853186-A Water-compatible reducible compounds and their use in analytical compositions and methods EASTMAN KODAK COMPANY (US) 1989-08-01 US disclosed
US-4746607-A MEDICAL DIAGNOSIS, DETECTION OF BACTERIA EASTMAN KODAK COMPANY (US) 1988-05-24 US disclosed
EP-0261931-A2 Rapid differentiation of fungi from bacteria using polyene antibiotics EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-03-30 EP disclosed
EP-0261934-A2 Rapid differentiation of bacteria using cyclic polypeptide antibiotics EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-03-30 EP disclosed
EP-0259133-A2 Use of organic buffers to reduce dehydroascorbic acid interference in analytical methods EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-03-09 EP disclosed
EP-0247848-A2 Water-compatible reducible compounds and their use in analytical compositions and methods EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-12-02 EP disclosed
EP-0190740-A2 Use of substituted quinone electron transfer agents in analytical determinations EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-08-13 EP disclosed