Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.39 |
| ▸ | CDC25B | P30305 | 6/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL305465 | 0.76 | PTPN1 (0.53) | PTPN1PARP15PARP10MAOBPTPN2 | |
| SCHEMBL8877502 | 0.69 | PARP10 (0.58) | PTPN1PARP15PARP10MAOBPTPN2 | |
| SCHEMBL7635956 | 0.68 | PTPN1 (0.45) | PTPN1PARP15PARP10MAOBPTPN2 | |
| SCHEMBL12443168 | 0.68 | PTPN1 (0.53) | PTPN1PARP15PARP10MAOBPTPN2 | |
| SCHEMBL15132934 | 0.67 | MAOB (0.59) | PARP15PARP10MAOBSCN3ASCN9A | |
| SCHEMBL8876327 | 0.67 | HDAC4 (0.58) | PTPN1MAOB | |
| SCHEMBL8876321 | 0.67 | HDAC4 (0.58) | PTPN1MAOB | |
| Netoglitazone SCHEMBL142658 | 0.67 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL20125595 | 0.67 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B | |
| Netoglitazone SCHEMBL29355960 | 0.67 | FFAR1 (0.55) | PTPN1PARP15PARP10PTPN2CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169037-A2 | USE OF INSULIN SENSITISERS FOR IMPROVING KETOSIS | Takeda Pharmaceutical Company Limited (JP) | 2002-01-09 | — | — | EP | claimed |
| WO-2000061127-A2 | USE OF INSULIN SENSITISERS FOR IMPROVING KETOSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-19 | — | — | WO | claimed |