Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.58 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.51 |
| ▸ | CDC25B | P30305 | 3/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21340831 | 0.86 | MAOB (0.65) | PARP10PARP15MAOBNPC1RAB9A | |
| SCHEMBL12443168 | 0.86 | PTPN1 (0.53) | PARP10PARP15PTPN1MAOBNPC1 | |
| SCHEMBL7239415 | 0.84 | MAOB (0.58) | PARP10PARP15PTPN1MAOBNPC1 | |
| SCHEMBL5397207 | 0.80 | PTPN1 (0.60) | PARP10PARP15PTPN1MAOBPTPN2 | |
| SCHEMBL8877320 | 0.80 | PTPN1 (0.64) | PARP10PARP15PTPN1MAOBPTPN2 | |
| SCHEMBL8876594 | 0.80 | PTPN1 (0.60) | PARP10PARP15PTPN1MAOBPTPN2 | |
| SCHEMBL5968422 | 0.79 | PTPN1 (0.50) | PARP10PARP15PTPN1MAOBNPC1 | |
| SCHEMBL4244280 | 0.79 | PTPN1 (0.56) | PARP10PARP15PTPN1MAOBNPC1 | |
| SCHEMBL31556124 | 0.79 | PTPN1 (0.56) | PARP10PARP15PTPN1MAOBNPC1 | |
| SCHEMBL21083437 | 0.79 | MAOB (0.55) | PARP10PARP15PTPN1MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594016-A | ANTIDIABETIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0604983-B1 | Naphthalene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-11-20 | — | — | EP | disclosed |
| EP-0604983-A1 | Naphthalene derivatives | Mitsubishi Chemical Corporation (JP) | 1994-07-06 | — | — | EP | disclosed |