SCHEMBL7514929

SCHEMBL7514929

CC(=O)ON1C(C)(C)CC(O)CC1(C)C

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.41
ESR1 P03372 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GAA P10253 2/20 0.34
MEN1 O00255 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13110304 0.83 TSHR (0.50) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL28364620 0.80 KMT2A (0.40) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL1138567 0.80 KMT2A (0.63) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL4325339 0.80 TSHR (0.55) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL987544 0.80 TSHR (0.55) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL13008698 0.80 TSHR (0.35) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL16341866 0.80 TSHR (0.48) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL12921994 0.79 TSHR (0.61) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL8503955 0.77 KMT2A (0.44) TSHRKMT2AALDH1A1ESR1HSD17B10
SCHEMBL1138474 0.77 TSHR (0.46) TSHRKMT2AALDH1A1ESR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1649566-B Stabilized body care products, household products, textiles and fabrics CIBA SC HOLDING AG 2010-05-26 CN claimed
CN-1649566-A Stabilized body care products, household products, textiles and fabrics CIBA SC HOLDING AG (CH) 2005-08-03 CN claimed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
EP-0365481-A1 Polymeric substrates stabilized with N-substituted hindered amines CIBA-GEIGY AG (CH) 1990-04-25 EP claimed
CN-103502528-A Method of dyeing polyester HUNTSMAN ADV MAT SWITZERLAND 2014-01-08 CN disclosed
US-8471031-B2 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2013-06-25 US disclosed
US-8471031-B2 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2013-06-25 US disclosed
EP-2253667-A1 POLYLACTIC ACID RESIN COMPOSITION Adeka Corporation (JP) 2010-11-24 EP disclosed
US-20100249401-A1 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2010-09-30 US disclosed
US-20100249401-A1 Process for the preparation of sterically hindered nitroxyl ethers BASF SE (DE) 2010-09-30 US disclosed
US-7358365-B2 Process for the controlled increase in the molecular weight of polyethylenes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-15 US disclosed
US-6500303-B1 DERIVATIVES OF 1-OXYL-2,2,6,6-TETRAMETHYL-PIPERIDIN-4-OL; PROTECTION FROM ULTRAVIOLET, FLUORESCENT AND SUN LIGHT EXPOSURE CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-31 US disclosed
US-5300647-A Light stabilizers for polyolefins, other polymers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP disclosed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed
EP-0365481-A1 Polymeric substrates stabilized with N-substituted hindered amines CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed
EP-0309400-A2 N-acyloxy hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249401-A1 Process for the preparation of sterically hindered nitroxyl ethers PPOX, CBR1, CBR3 TSHR 3332/4885KMT2A 2110/4885ALDH1A1 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.