Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400448 | 0.81 | OPRM1 (0.48) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL13411321 | 0.74 | OPRM1 (0.50) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL3454555 | 0.74 | SPHK1 (0.47) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL11287487 | 0.73 | GRIK1 (0.47) | SPHK1LAP3MAPTGRIK1GRIK2 | |
| SCHEMBL3694779 | 0.72 | OPRM1 (0.52) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL28458489 | 0.72 | OPRM1 (0.52) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL27221680 | 0.72 | OPRM1 (0.52) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL11301482 | 0.70 | OPRM1 (0.50) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL21603627 | 0.70 | OPRM1 (0.50) | OPRM1SPHK1CYP2D6LMNATP53 | |
| SCHEMBL11291220 | 0.70 | OPRM1 (0.50) | OPRM1SPHK1CYP2D6LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448047-B2 | Sample processing to release nucleic acids for direct detection | APPLIED GENE TECHNOLOGIES, INC. | 2002-09-10 | — | — | US | disclosed |
| US-6423497-B1 | LABELING PREFERENTIAL NUCLEOTIDE SEQUENCES; OBTAIN NUCLEIC ACIDS, INCUBATE IN AMPLIFICATION MIXTURE WITH LABEL AND BINDING AGENT, EXPOSE TO LIGHT, RECOVER PRODUCT | APPLIED GENE TECHNOLOGIES, INC. | 2002-07-23 | — | — | US | disclosed |
| US-20020061537-A1 | Stabilization of nucleic acid amplification cocktails | DATTAGUPTA NANIBHUSHAN (US) | 2002-05-23 | — | — | US | disclosed |
| US-6379930-B1 | Stabilization of nucleic acid amplification cocktails | APPLIED GENE TECHNOLOGIES, INC. | 2002-04-30 | — | — | US | disclosed |
| EP-1192272-A2 | METHOD OF LABELING A NUCLEIC ACID AMPLICON WITH SIMULTANEOUS CONTAMINATION PREVENTION | Applied Gene Technologies, Inc. (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2002014548-A1 | COMPOSITIONS AND METHODS FOR NUCLEIC ACIDS SAMPLE PROCESSING AND AMPLIFICATION | APPLIED GENE TECHNOLOGIES, INC. (US) | 2002-02-21 | — | — | WO | disclosed |
| US-20010031473-A1 | Sample processing to release nucleic acids for direct detection | DATTAGUPTA NANIBHUSHAN (US) | 2001-10-18 | — | — | US | disclosed |
| US-6242188-B1 | Sample processing to release nucleic acids for direct detection | APPLIED GENE TECHNOLOGIES, INC. | 2001-06-05 | — | — | US | disclosed |
| US-6187566-B1 | COMPLEXES | APPLIED GENE TECHNOLOGIES, INC. | 2001-02-13 | — | — | US | disclosed |
| WO-2000053809-A2 | METHOD OF LABELING A NUCLEIC ACID AMPLICON WITH SIMULTANEOUS CONTAMINATION PREVENTION | APPLIED GENE TECHNOLOGIES, INC. (US) | 2000-09-14 | — | — | WO | disclosed |