Malonic Acid

Malonic Acid

SCHEMBL7515446

C=C(C)C(=O)OC(C)C.C=C(C)C(=O)OC(C)C.O=C(O)CC(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.45
ALDH1A1 P00352 2/20 0.44
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
THRB P10828 1/20 0.34
TGFBR1 P36897 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
ADRA1A P35348 1/20 0.33
PDE4D Q08499 1/20 0.33
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL7515703 0.88 TSHR (0.45) TSHRALDH1A1GAASMN1; SMN2THRB
SCHEMBL21772350 0.87 TSHR (0.52) TSHRALDH1A1GAASMN1; SMN2THRB
SCHEMBL15253 0.87
Methacrylic Acid SCHEMBL6131252 0.85 TSHR (0.46) TSHRALDH1A1GAASMN1; SMN2THRB
Oxalic Acid SCHEMBL7518307 0.85 TSHR (0.46) TSHRALDH1A1GAASMN1; SMN2THRB
Benzene SCHEMBL27682798 0.85 TSHR (0.46) TSHRALDH1A1GAASMN1; SMN2THRB
Fluoride SCHEMBL28010993 0.84 TSHR (0.50) TSHRALDH1A1GAASMN1; SMN2THRB
SCHEMBL3838892 0.84 TSHR (0.50) TSHRALDH1A1GAASMN1; SMN2THRB
Water SCHEMBL27744037 0.84 TSHR (0.50) TSHRALDH1A1GAASMN1; SMN2THRB
Ethylene SCHEMBL27854424 0.84 TSHR (0.50) TSHRALDH1A1GAASMN1; SMN2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487084-B1 Image forming method and apparatus CANON KK (JP) 2002-01-30 EP disclosed
US-5864406-A Method and apparatus for forming halftone images on organic-silver-salt-based printing plates CANON KABUSHIKI KAISHA (JP) 1999-01-26 US disclosed
EP-0487084-A2 Image forming method and apparatus CANON KABUSHIKI KAISHA (JP) 1992-05-27 EP disclosed
US-5073791-A IMAGE FORMING DEVICE CANON KABUSHIKI KAISHA (JP) 1991-12-17 US disclosed
EP-0410803-A2 Image forming device CANON KABUSHIKI KAISHA (JP) 1991-01-30 EP disclosed