Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL7515446 | 0.88 | TSHR (0.45) | TSHRLMNAALDH1A1THRBHCAR2 | |
| SCHEMBL21772350 | 0.87 | TSHR (0.52) | TSHRLMNAALDH1A1KDM4ETHRB | |
| SCHEMBL15253 | 0.87 | — | — | |
| Succinic Acid SCHEMBL11592869 | 0.86 | TSHR (0.44) | TSHRLMNASLC15A2ALDH1A1EGLN1 | |
| Methacrylic Acid SCHEMBL6131252 | 0.85 | TSHR (0.46) | TSHRLMNAALDH1A1KDM4ETHRB | |
| Benzene SCHEMBL27682798 | 0.85 | TSHR (0.46) | TSHRLMNAALDH1A1CYP1A2THRB | |
| Oxalic Acid SCHEMBL7518307 | 0.85 | TSHR (0.46) | TSHRLMNAALDH1A1KDM4ETHRB | |
| SCHEMBL3838892 | 0.84 | TSHR (0.50) | TSHRLMNAALDH1A1KDM4ETHRB | |
| Fluoride SCHEMBL28010993 | 0.84 | TSHR (0.50) | TSHRLMNAALDH1A1KDM4ETHRB | |
| Water SCHEMBL27744037 | 0.84 | TSHR (0.50) | TSHRLMNAALDH1A1KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487084-B1 | Image forming method and apparatus | CANON KK (JP) | 2002-01-30 | — | — | EP | disclosed |
| US-5864406-A | Method and apparatus for forming halftone images on organic-silver-salt-based printing plates | CANON KABUSHIKI KAISHA (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0487084-A2 | Image forming method and apparatus | CANON KABUSHIKI KAISHA (JP) | 1992-05-27 | — | — | EP | disclosed |
| US-5073791-A | IMAGE FORMING DEVICE | CANON KABUSHIKI KAISHA (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0410803-A2 | Image forming device | CANON KABUSHIKI KAISHA (JP) | 1991-01-30 | — | — | EP | disclosed |