Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.75 |
| ▸ | MMP1 | P03956 | 7/20 | 0.75 |
| ▸ | MMP9 | P14780 | 2/20 | 0.75 |
| ▸ | MMP3 | P08254 | 10/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7445514 | 0.90 | MMP2 (0.73) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7555583 | 0.90 | MMP2 (0.73) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7551229 | 0.87 | MMP2 (0.76) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7448855 | 0.86 | MMP2 (0.75) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7448676 | 0.85 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7550762 | 0.85 | MMP2 (0.82) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7576625 | 0.85 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7449871 | 0.85 | MMP2 (0.73) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7505186 | 0.85 | MMP2 (0.65) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7503936 | 0.85 | MMP2 (0.75) | MMP2MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001930-B1 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2002-12-04 | — | — | EP | claimed |