Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 20/20 | 0.82 |
| ▸ | MMP1 | P03956 | 12/20 | 0.82 |
| ▸ | MMP9 | P14780 | 5/20 | 0.82 |
| ▸ | MMP3 | P08254 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448676 | 0.90 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7576625 | 0.90 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7551229 | 0.86 | MMP2 (0.76) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7515464 | 0.85 | MMP2 (0.75) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7448855 | 0.85 | MMP2 (0.75) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7449871 | 0.85 | MMP2 (0.73) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7508422 | 0.84 | MMP2 (1.00) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7449802 | 0.83 | MMP2 (0.73) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7448565 | 0.83 | MMP2 (0.58) | MMP2MMP1MMP9MMP3 | |
| SCHEMBL7576504 | 0.82 | MMP2 (0.79) | MMP2MMP1MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001930-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999006361-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | claimed |
| EP-1001930-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | Abbott Laboratories (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006361-A2 | N-HYDROXYFORMAMIDE DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 1999-02-11 | — | — | WO | disclosed |