Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1347900 | 0.84 | CNR1 (0.55) | NR3C2CNR1EPHX2NR1H4FAAH | |
| SCHEMBL10243641 | 0.83 | BCL2 (0.55) | NR3C2CNR1CSF1RFLT1FLT3 | |
| SCHEMBL10243328 | 0.83 | BCL2 (0.55) | NR3C2CNR1CSF1RFLT1FLT3 | |
| SCHEMBL13929187 | 0.82 | ERN1 (0.52) | NR3C2CNR1CSF1RFLT1FLT3 | |
| SCHEMBL27352380 | 0.82 | ERN1 (0.54) | CNR1CSF1RFLT1FLT3TRPV1 | |
| SCHEMBL2570385 | 0.82 | NOS1 (0.54) | PARP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1345554 | 0.81 | DPP4 (0.52) | NR3C2CNR1CSF1RFLT1FLT3 | |
| SCHEMBL1345869 | 0.81 | ALDH1A1 (0.51) | NR3C2CNR1CSF1RFLT1FLT3 | |
| SCHEMBL1348033 | 0.81 | CSF1R (0.57) | NR3C2CNR1CSF1RFLT1FLT3 | |
| SCHEMBL30504326 | 0.81 | ERN1 (0.53) | NR3C2CNR1CSF1RFLT1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138209-B2 | Substituted picolinamides as MAO-B inhibitors useful for treating obesity | JENRIN DISCOVERY, INC. (US) | 2012-03-20 | — | — | US | disclosed |