Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559873 | 0.83 | EGFR (0.48) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL12547281 | 0.82 | KMT2A (0.51) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL28985146 | 0.80 | KMT2A (0.71) | ALDH1A1HPGDKMT2AMEN1HTT | |
| SCHEMBL537056 | 0.77 | LMNA (0.70) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL12548398 | 0.77 | KMT2A (0.43) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL6900506 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTKMT2ALMNA | |
| SCHEMBL21814404 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTKMT2ALMNA | |
| SCHEMBL25252134 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTKMT2ALMNA | |
| SCHEMBL2182699 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTKMT2ALMNA | |
| SCHEMBL14586581 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |
| EP-1165492-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | Pharmacor Inc. (CA) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059867-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR INC. (CA) | 2000-10-12 | — | — | WO | disclosed |