Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4777238 | 0.97 | CCR5 (0.71) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4777547 | 0.88 | CCR5 (0.79) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4777251 | 0.87 | CCR5 (0.68) | CCR5 | |
| SCHEMBL4773722 | 0.86 | CCR5 (0.75) | CCR5 | |
| SCHEMBL4778085 | 0.86 | CCR5 (1.00) | CCR5 | |
| SCHEMBL4779011 | 0.85 | CCR5 (0.84) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4776673 | 0.85 | CCR5 (0.75) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4771581 | 0.85 | CCR5 (0.91) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4776716 | 0.84 | CCR5 (0.77) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4768182 | 0.84 | CCR5 (0.74) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1220842-A1 | CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-10 | — | — | EP | disclosed |
| WO-2001025200-A1 | CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-12 | — | — | WO | disclosed |