Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716250 | 0.88 | ALDH1A1 (0.46) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL5932136 | 0.86 | ALDH1A1 (0.45) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL5932125 | 0.86 | ALDH1A1 (0.44) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL17209569 | 0.85 | ALOX5 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL5933190 | 0.85 | ALDH1A1 (0.43) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL8961331 | 0.85 | ALOX5 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL5655815 | 0.85 | ALDH1A1 (0.43) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL5933199 | 0.85 | ALDH1A1 (0.43) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL5655825 | 0.85 | ALDH1A1 (0.43) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA | |
| SCHEMBL8467415 | 0.85 | ALOX5 (0.48) | ALDH1A1CYP2C9CYP2C19CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | claimed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | claimed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | disclosed |
| EP-0592552-B1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | DU PONT (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5596114-A | ENANTIOSELECTIVE HYDROGENATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5565593-A | FERROCENYL-1,1'-BIS(DIETHYPHOSPHONITE); CHEMICAL INTERMEDIATES FOR PREPERATION OF PHOSPHOLANE LIGANDS AND CHIRAL COMPLEXES, USEFUL AS CATALYSTS FOR CARRYING OUT ENANTIOSELECTIVE REACTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| US-5559267-A | ENANTIOMORPHS, STEREOCHEMICAL CONTROL AND ASSYMETRIC INDUCTION, HYDROGENATION OF UNSATURATED ESTERS, COORDINATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| US-5532395-A | HYDROGENATION CATALYSTS ) | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-07-02 | — | — | US | disclosed |
| US-5386061-A | Reacting a bis(primary phosphine in the presence of a strong base with a cyclic sulfate; cyclization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| US-5329015-A | Catalysts for stereospecific reactions | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| WO-1993001199-A1 | CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| US-5171892-A | Chiral phospholanes via chiral 1,4-diol cyclic sulfates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-15 | — | — | US | disclosed |