Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27385115 | 0.76 | TRPM8 (0.43) | EPHX1TACR1 | |
| SCHEMBL4180733 | 0.74 | EPHX1 (0.51) | EPHX1TACR1 | |
| SCHEMBL17336172 | 0.71 | CRBN (0.51) | CRBNDDB1 | |
| SCHEMBL5742102 | 0.71 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL30694233 | 0.71 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL27832973 | 0.71 | CPN1 (0.45) | EPHX1TACR1 | |
| SCHEMBL20362309 | 0.70 | HDAC1 (0.39) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL30694225 | 0.70 | CRBN (0.56) | CRBNDDB1 | |
| Hydrochloric Acid SCHEMBL31551114 | 0.70 | CRBN (0.56) | CRBNDDB1 | |
| SCHEMBL4022907 | 0.69 | EPHX1 (0.46) | EPHX1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452012-B1 | USEFULL CHEMICAL INTERMEDIATES FOR SYNTHESIS OF NEUROKININ ANTAGONISTS | SANOFI-SYNTHELABO (FR) | 2002-09-17 | — | — | US | disclosed |