SCHEMBL7516374

SCHEMBL7516374

CC=Cc1ccccc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
SOS1 Q07889 1/20 0.57
MAOB P27338 1/20 0.56
CYP19A1 P11511 2/20 0.55
RAB9A P51151 4/20 0.54
ALDH1A1 P00352 3/20 0.54
ATM Q13315 2/20 0.54
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
NPSR1 Q6W5P4 1/20 0.51
NPC1 O15118 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KDM4E B2RXH2 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
LMNA P02545 2/20 0.50
HSP90AA1 P07900 1/20 0.50
HSD17B10 Q99714 1/20 0.50
AR P10275 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7527194 1.00 MAPT (0.61) MAPTSOS1MAOBCYP19A1RAB9A
SCHEMBL415690 1.00 MAPT (0.61) MAPTSOS1MAOBCYP19A1RAB9A
Bicarbonate SCHEMBL27446001 0.93 MAPT (0.68) MAPTSOS1MAOBRAB9AALDH1A1
SCHEMBL11049170 0.87 MAPT (0.69) MAPTSOS1MAOBCYP19A1RAB9A
SCHEMBL14935499 0.87 MAPT (0.69) MAPTSOS1MAOBCYP19A1RAB9A
SCHEMBL9978289 0.87 MAPT (0.69) MAPTSOS1MAOBCYP19A1RAB9A
SCHEMBL9622795 0.87 SOS1 (0.61) MAPTSOS1MAOBCYP19A1RAB9A
SCHEMBL9622793 0.87 SOS1 (0.61) MAPTSOS1MAOBCYP19A1RAB9A
SCHEMBL11296000 0.85 MAPT (0.67) MAPTSOS1MAOBCYP19A1RAB9A
SCHEMBL11299049 0.85 MAPT (0.67) MAPTSOS1MAOBCYP19A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108329248-B Preparation method of 2-methylindoline 北京成宇化工有限公司 2020-10-30 CN disclosed
CN-110452172-A A kind of synthetic method of benzo caprolactam ASTATECH CHENGDU BIOPHARMACEUTICAL CORP 2019-11-15 CN disclosed
CN-104529683-B The preparation method of 1-phenylpropene derivatives 陕西师范大学 2016-08-17 CN disclosed
CN-103304440-B 3-[2-(aryl propylenine)hydrazino]-ethyl benzoate compound and application thereof UNIV EAST CHINA SCIENCE & TECH 2015-04-15 CN disclosed
CN-103553973-B o-nitroaroyl beta-chloroethyl nitrosourea compounds, preparation and use thereof LANZHOU WEIYI BIOLOGY TECHNOLOGY DEV CO LTD 2015-01-14 CN disclosed
CN-103553973-A o-nitroaroyl beta-chloroethyl nitrosourea compounds, preparation and use thereof LANZHOU WEIYI BIOLOGY TECHNOLOGY DEV CO LTD 2014-02-05 CN disclosed
CN-103304440-A 3-[2-(aryl propylenine)hydrazino]-ethyl benzoate compound and application thereof UNIV EAST CHINA SCIENCE & TECH 2013-09-18 CN disclosed
CN-103254027-A Method for preparing 1,2-diphenyl propylene compound SINOCHEM CORP 2013-08-21 CN disclosed
CN-102399310-B Composition and method used for inhibiting premature polymerization GEN ELECTRIC 2013-07-24 CN disclosed
CN-102702113-A 5-Fluorouracil derivative and preparation method and uses UNIV LANGZHOU 2012-10-03 CN disclosed
EP-0944563-B1 SUBSTANCE MIXTURES CONTAINING STABILIZERS AND COMPOUNDS CONTAINING VINYL GROUPS BASF AG (DE) 2002-04-03 EP disclosed
EP-1179529-A1 NOVEL HYDROXAMIC ACID DERIVATIVES Daiichi Fine Chemical Co., Ltd. (JP) 2002-02-13 EP disclosed
US-6200460-B1 MIXTURE COMPRISING VINYL AROMATIC COMPOUND, ACTIVE AMOUNT OF MIXTURE WHICH INHIBITS THE PREMATURE POLYMERIZATION OF SAID COMPOUND COMPRISING NOXYL COMPOUND, IRON COMPOUND, OPTIONALLY NITRO COMPOUNDS AND COSTABILIZERS BASF AKTIENGESELLSCHAFT (DE) 2001-03-13 US disclosed
US-6143205-A A MIXTRUE COMPRISES A VINYL-CONTAINING MONOMERS, AND A MIXTURE OF PREMATURE POLYMERIZATION INHIBITOR OF MONOMERS DURING PURIFICATION OR DISTILLATION COMPRISING A N-OXYL COMPOUND OF SECONDARY AMINE AND A NITRO COMPOUND BASF AKTIENGESELLSCHAFT (DE) 2000-11-07 US disclosed
EP-1038864-A1 NOVEL METALLOPROTEINASE INHIBITORS FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 2000-09-27 EP disclosed
CN-1227533-A Substance mixture comprising a vinyl compound and a stabilizer BASF AG (DE) 1999-09-01 CN disclosed
EP-0350069-B1 METHOD FOR OXIDIZING UNSATURATED AROMATIC COMPOUNDS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
US-4967009-A REACTING UNSATURATED AROMATIC COMPOUNDS WITH AROMATIC IODOSYL COMPOUNDS TO YIELD AROMATIC ALDEHYDES OR KETONES NIPPON PETROCHEMICALS CO., LTD. (JP) 1990-10-30 US disclosed
EP-0350069-A2 Method for oxidizing unsaturated aromatic compounds NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-01-10 EP disclosed
EP-0104863-B1 LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE FUJI PHOTO FILM CO., LTD. (JP) 1989-05-03 EP disclosed