Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622793 | 1.00 | SOS1 (0.61) | SOS1MAPTNPSR1MAOBALDH1A1 | |
| SCHEMBL5440780 | 0.91 | SOS1 (0.71) | SOS1MAPTNPSR1MAOBALDH1A1 | |
| SCHEMBL5440784 | 0.91 | SOS1 (0.71) | SOS1MAPTNPSR1MAOBALDH1A1 | |
| SCHEMBL7527194 | 0.87 | MAPT (0.61) | SOS1MAPTNPSR1MAOBALDH1A1 | |
| SCHEMBL7516374 | 0.87 | MAPT (0.61) | SOS1MAPTNPSR1MAOBALDH1A1 | |
| SCHEMBL415690 | 0.87 | MAPT (0.61) | SOS1MAPTNPSR1MAOBALDH1A1 | |
| SCHEMBL10405612 | 0.84 | SOS1 (0.63) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL6156770 | 0.84 | SOS1 (0.50) | SOS1MAPTNPSR1MAOBALDH1A1 | |
| SCHEMBL10405613 | 0.84 | SOS1 (0.63) | SOS1MAPTMAOBALDH1A1RAB9A | |
| SCHEMBL9978289 | 0.82 | MAPT (0.69) | SOS1MAPTNPSR1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |