Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527194 | 1.00 | MAPT (0.61) | MAPTSOS1MAOBCYP19A1RAB9A | |
| SCHEMBL7516374 | 1.00 | MAPT (0.61) | MAPTSOS1MAOBCYP19A1RAB9A | |
| Bicarbonate SCHEMBL27446001 | 0.93 | MAPT (0.68) | MAPTSOS1MAOBRAB9AALDH1A1 | |
| SCHEMBL11049170 | 0.87 | MAPT (0.69) | MAPTSOS1MAOBCYP19A1RAB9A | |
| SCHEMBL14935499 | 0.87 | MAPT (0.69) | MAPTSOS1MAOBCYP19A1RAB9A | |
| SCHEMBL9978289 | 0.87 | MAPT (0.69) | MAPTSOS1MAOBCYP19A1RAB9A | |
| SCHEMBL9622795 | 0.87 | SOS1 (0.61) | MAPTSOS1MAOBCYP19A1RAB9A | |
| SCHEMBL9622793 | 0.87 | SOS1 (0.61) | MAPTSOS1MAOBCYP19A1RAB9A | |
| SCHEMBL11296000 | 0.85 | MAPT (0.67) | MAPTSOS1MAOBCYP19A1RAB9A | |
| SCHEMBL11299049 | 0.85 | MAPT (0.67) | MAPTSOS1MAOBCYP19A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | claimed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | claimed |
| US-20180011405-A1 | RESIST UNDERLAYER FILM COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING RESIST UNDERLAYER FILM, AND COMPOUND FOR RESIST UNDERLAYER FILM COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-01-11 | — | — | US | disclosed |
| US-9328061-B2 | Simple organic molecules as catalysts for practical and efficient enantioselective synthesis of amines and alcohols | TRUSTEES OF BOSTON COLLEGE (US) | 2016-05-03 | — | — | US | disclosed |
| US-9290484-B2 | Furyl and thienyl triazole derivatives and therapeutic uses thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-03-22 | — | — | US | disclosed |
| US-9290484-B2 | Furyl and thienyl triazole derivatives and therapeutic uses thereof | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-03-22 | — | — | US | disclosed |
| US-20160045528-A1 | COMBINATION THERAPY FOR TREATING A PARAMYXOVIRUS | ALIOS BIOPHARMA, INC. | 2016-02-18 | — | — | US | disclosed |
| US-20150057451-A1 | SIMPLE ORGANIC MOLECULES AS CATALYSTS FOR PRACTICAL AND EFFICIENT ENANTIOSELECTIVE SYNTHESIS OF AMINES AND ALCOHOLS | NATIONAL INSTITUTES OF HEALTH, U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, U.S. GOVERNMENT | 2015-02-26 | — | — | US | disclosed |
| US-8895497-B2 | Cathepsin S inhibitors | DCB-USA, LLC (US) | 2014-11-25 | — | — | US | disclosed |
| US-20140243381-A1 | FURYL AND THIENYL TRIAZOLE DERIVATIVES AND THERAPEUTIC USES THEREOF | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2014-08-28 | — | — | US | disclosed |
| US-20140243381-A1 | FURYL AND THIENYL TRIAZOLE DERIVATIVES AND THERAPEUTIC USES THEREOF | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2014-08-28 | — | — | US | disclosed |
| US-20070203236-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | UNITED STATES GOVERNMENT | 2007-08-30 | — | — | US | disclosed |
| US-20070032503-A1 | Method of preparation of azaindole derivatives | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2007-02-08 | — | — | US | disclosed |
| WO-2003035057-A1 | INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | FERRING B.V. (NL) | 2003-05-01 | — | — | WO | disclosed |
| EP-1179529-A1 | NOVEL HYDROXAMIC ACID DERIVATIVES | Daiichi Fine Chemical Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |
| EP-0350069-B1 | METHOD FOR OXIDIZING UNSATURATED AROMATIC COMPOUNDS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4967009-A | REACTING UNSATURATED AROMATIC COMPOUNDS WITH AROMATIC IODOSYL COMPOUNDS TO YIELD AROMATIC ALDEHYDES OR KETONES | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1990-10-30 | — | — | US | disclosed |
| EP-0350069-A2 | Method for oxidizing unsaturated aromatic compounds | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| EP-0104863-B1 | LIGHT-SENSITIVE PLANOGRAPHIC PRINTING PLATE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203236-A1 | NOVEL ANTAGONISTS OF THE HUMAN FATTY ACID SYNTHASE THIOESTERASE | FADS2, ACOT7, FADS1 | MAPT 4500/4885SOS1 3772/4885MAOB 1269/4885 |
| US-20150057451-A1 | SIMPLE ORGANIC MOLECULES AS CATALYSTS FOR PRACTICAL AND EFFICIENT ENANTIOSELECTIVE SYNTHESIS OF AMINES AND ALCOHOLS | ADH1C, ADH5, ADH1A | MAPT 1268/4885SOS1 2864/4885MAOB 10/4885 |
| US-20070032503-A1 | Method of preparation of azaindole derivatives | TPMT, HAVCR2, CYP3A43 | MAPT 3261/4885SOS1 4636/4885MAOB 28/4885 |
| US-20140243381-A1 | FURYL AND THIENYL TRIAZOLE DERIVATIVES AND THERAPEUTIC USES THEREOF | NOS3, NOS2, NOS1 | MAPT 3911/4885SOS1 3422/4885MAOB 343/4885 |
| US-20160045528-A1 | COMBINATION THERAPY FOR TREATING A PARAMYXOVIRUS | MAVS, EIF2AK2, SARS1 | MAPT 4258/4885SOS1 4459/4885MAOB 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.