Acrylamide

Acrylamide

SCHEMBL7516464

C=CC(N)=O.CC(=O)CCC(C)=O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
TSHR P16473 5/20 0.61
FGFR4 P22455 1/20 0.61
LMNA P02545 3/20 0.46
SLC15A2 Q16348 1/20 0.46
POLB P06746 1/20 0.41
PAOX Q6QHF9 2/20 0.39
ALOX15 P16050 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
ACHE P22303 1/20 0.33
TP53 P04637 1/20 0.33
TRPA1 O75762 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Levulinic Acid SCHEMBL6521215 0.91 LMNA (0.64) ALDH1A1TSHRFGFR4LMNASLC15A2
Acrylamide SCHEMBL1032337 0.85 ALDH1A1 (0.50) ALDH1A1TSHRFGFR4LMNASLC15A2
Acrylamide SCHEMBL11529233 0.83 ALDH1A1 (0.61) ALDH1A1TSHRFGFR4LMNAPOLB
Acrylamide SCHEMBL27601376 0.83 ALDH1A1 (0.61) ALDH1A1TSHRFGFR4LMNAPOLB
Acrylamide SCHEMBL28200115 0.83 ALDH1A1 (0.61) ALDH1A1TSHRFGFR4LMNAPOLB
Acrylamide SCHEMBL3392716 0.82
Acrylamide SCHEMBL35469 0.82 ALDH1A1 (0.79) ALDH1A1TSHRFGFR4LMNAPOLB
Acrylamide SCHEMBL9936680 0.82 ALDH1A1 (0.79) ALDH1A1TSHRFGFR4LMNAPOLB
Acrylamide SCHEMBL9304706 0.82 ALDH1A1 (0.79) ALDH1A1TSHRFGFR4LMNAPOLB
Acrylamide SCHEMBL679118 0.82 ALDH1A1 (0.79) ALDH1A1TSHRFGFR4LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020146515-A1 Aqueous compositions for coating metal components BASF AKTIENGESELLSCHAFT (DE) 2002-10-10 US disclosed