⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90093 | 0.75 | — | — | |
| SCHEMBL10445746 | 0.69 | PIK3CD (0.31) | — | |
| SCHEMBL75994 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL9080353 | 0.67 | TSHR (0.37) | — | |
| SCHEMBL90461 | 0.67 | — | — | |
| SCHEMBL6307656 | 0.67 | — | — | |
| SCHEMBL1921235 | 0.67 | — | — | |
| SCHEMBL1546247 | 0.65 | — | — | |
| SCHEMBL13858441 | 0.65 | PIK3CD (0.31) | — | |
| SCHEMBL4078168 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013061247-A1 | NOVEL PROCESS FOR THE PREPARATION OF ASENAPINE | ALEMBIC PHARMACEUTICALS LIMITED (IN) | 2013-05-02 | — | — | WO | claimed |
| US-20100234618-A1 | Process for the Preparation of Asenapine and Intermediate Products Used in Said Process | N.V. ORGANON (NL) | 2010-09-16 | — | — | US | claimed |
| US-7750167-B2 | Process for the preparation of asenapine and intermediate products used in said process | N.V. ORGANON (NL) | 2010-07-06 | — | — | US | claimed |
| EP-2044076-B1 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS. | ORGANON NV (NL) | 2009-10-14 | — | — | EP | claimed |
| EP-2044076-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS. | N.V. Organon (NL) | 2009-04-08 | — | — | EP | claimed |
| US-20080009619-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS | N.V. ORGANON (NL) | 2008-01-10 | — | — | US | claimed |
| WO-2008003460-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS. | N.V. ORGANON (NL) | 2008-01-10 | — | — | WO | claimed |
| EP-3897622-B1 | ARGINASE INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2026-01-14 | — | — | EP | disclosed |
| US-12240867-B2 | Arginase inhibitors and methods of use | MERCK SHARP & DOHME LLC (US) | 2025-03-04 | — | — | US | disclosed |
| US-11958858-B2 | Method for preparation of Asenapine | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2024-04-16 | — | — | US | disclosed |
| US-20230242478-A1 | AGONISTS OF ROR GAMMAt | BRISTOL MYERS SQUIBB CO (US) | 2023-08-03 | — | — | US | disclosed |
| US-20230159549-A1 | METHOD FOR PREPARATION OF ASENAPINE | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230159549-A1 | METHOD FOR PREPARATION OF ASENAPINE | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20080194549-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-08-14 | — | — | US | disclosed |
| US-20080045493-A1 | Heterocyclic Compounds Suitable For Treating Disorders That Respond To Modulation Of The Dopamine D3 Receptor | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2008-02-21 | — | — | US | disclosed |
| US-20080009619-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS | N.V. ORGANON (NL) | 2008-01-10 | — | — | US | disclosed |
| US-20080009619-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS | N.V. ORGANON (NL) | 2008-01-10 | — | — | US | disclosed |
| WO-2008003460-A1 | PROCESS FOR THE PREPARATION OF ASENAPINE AND INTERMEDIATE PRODUCTS USED IN SAID PROCESS. | N.V. ORGANON (NL) | 2008-01-10 | — | — | WO | disclosed |
| US-20070232653-A1 | Process for the preparation of enantiomerically enriched cyclic beta-aryl or heteroaryl carbocyclic acids | HOFFMANN-LA ROCHE INC. | 2007-10-04 | — | — | US | disclosed |
| US-20070232653-A1 | Process for the preparation of enantiomerically enriched cyclic beta-aryl or heteroaryl carbocyclic acids | HOFFMANN-LA ROCHE INC. | 2007-10-04 | — | — | US | disclosed |