Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 15/20 | 0.50 |
| ▸ | CPT1B | Q92523 | 11/20 | 0.49 |
| ▸ | CPT2 | P23786 | 4/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752431 | 0.86 | CPT1A (0.67) | CPT1ACPT1BCPT2 | |
| SCHEMBL751620 | 0.81 | CPT1A (0.76) | CPT1ACPT1BCPT2 | |
| SCHEMBL753134 | 0.80 | CPT1A (0.54) | CPT1ACPT1BCPT2 | |
| SCHEMBL751981 | 0.79 | CPT1A (0.49) | CPT1ACPT1BCPT2ALPL | |
| SCHEMBL13571495 | 0.78 | CPT1A (0.66) | CPT1ACPT1BCPT2 | |
| SCHEMBL753938 | 0.74 | CPT1A (0.65) | CPT1ACPT1BCPT2 | |
| SCHEMBL754242 | 0.73 | CPT1A (0.59) | CPT1ACPT1BCPT2ALPL | |
| SCHEMBL754865 | 0.72 | CPT1A (0.77) | CPT1ACPT1BCPT2ALPL | |
| SCHEMBL13571747 | 0.72 | CPT1A (0.68) | CPT1ACPT1BCPT2 | |
| SCHEMBL28393943 | 0.68 | ALDH1A1 (0.69) | GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996563-B1 | HETEROBICYCLIC SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DIABETES | HOFFMANN LA ROCHE (CH) | 2012-03-21 | — | — | EP | claimed |