SCHEMBL7516655

SCHEMBL7516655

C(OCC1CO1)C1CO1.CCCC(CO)CC(CO)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7521562 0.88 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL7518389 0.88 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL7520972 0.85 TSHR (0.41) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL7526414 0.84 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL7529239 0.80 TSHR (0.38) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL7516664 0.79 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL4609549 0.79 TSHR (0.42) ALDH1A1TSHR
SCHEMBL7525287 0.75 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
Ethohexadiol SCHEMBL6306010 0.75 LMNA (0.59) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL14891221 0.74 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0911326-B1 DIGLYCIDYL ETHERS KYOWA YUKA KK (JP) 2002-01-30 EP disclosed
US-6048956-A DIGLYCIDYL ETHERS OF DIOLS KYOWA YUKA CO., LTD. (JP) 2000-04-11 US disclosed
EP-0911326-A1 DIGLYCIDYL ETHERS Kyowa Yuka Co., Ltd. (JP) 1999-04-28 EP disclosed