Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445239 | 0.77 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR6RET | |
| SCHEMBL3627507 | 0.76 | HTR2A (0.37) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL7772298 | 0.73 | SIGMAR1 (0.39) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| SCHEMBL4457342 | 0.70 | HTR2A (0.36) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| SCHEMBL7615275 | 0.67 | HTR2A (0.34) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| SCHEMBL2777171 | 0.66 | HTR2A (0.33) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| SCHEMBL1065902 | 0.66 | HTR2A (0.33) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| SCHEMBL8666606 | 0.66 | RET (0.34) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| SCHEMBL9069738 | 0.66 | HTR2A (0.34) | SIGMAR1HTR2AHTR6KDM4ELMNA | |
| SCHEMBL8681705 | 0.66 | SIGMAR1 (0.32) | SIGMAR1HTR2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1167393-A1 | CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |