Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615275 | 0.84 | HTR2A (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL7644941 | 0.81 | HTR6 (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL7770537 | 0.81 | HTR6 (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL3627507 | 0.79 | HTR2A (0.37) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL8666606 | 0.79 | RET (0.34) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL1065902 | 0.79 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL2777171 | 0.79 | HTR2A (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL8681705 | 0.78 | SIGMAR1 (0.32) | HTR2AHTR6SIGMAR1 | |
| SCHEMBL6440494 | 0.77 | HTR6 (0.33) | HTR2AHTR6SIGMAR1KDM4EBRD4 | |
| SCHEMBL437961 | 0.77 | SIGMAR1 (0.31) | HTR2AHTR6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131705-A1 | Practical, Cost-Effective Synthesis of Ubiquinones | ZYMES, LLC | 2009-05-21 | — | — | US | disclosed |
| EP-1968608-A2 | PRACTICAL, COST-EFFECTIVE SYNTHESIS OF UBIQUINONES | Zymes, LLC (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-10 | — | — | US | disclosed |
| WO-2008019196-A2 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHSIS OF UBIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-14 | — | — | WO | disclosed |
| WO-2007078679-A2 | PRACTICAL, COST-EFFECTIVE SYNTHESIS OF UBIQUINONES | ZYMES, LLC (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20060167289-A1 | Practical, cost-effective synthesis of ubiquinones | ZYMES, LLC (US) | 2006-07-27 | — | — | US | disclosed |
| US-6927184-B1 | Method of producing microfiber nonwovens that contain cycloolefin polymers | TICONA GMBH (DE) | 2005-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | NDUFA10, NDUFB10, NDUFV1 | HTR2A 2418/4885HTR6 2149/4885SIGMAR1 2899/4885 |
| US-20060167289-A1 | Practical, cost-effective synthesis of ubiquinones | SQOR, NDUFS6, NDUFS5 | HTR2A 2734/4885HTR6 1713/4885SIGMAR1 4443/4885 |
| US-20090131705-A1 | Practical, Cost-Effective Synthesis of Ubiquinones | SQOR, NDUFS6, NDUFS5 | HTR2A 2734/4885HTR6 1713/4885SIGMAR1 4443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.