Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.33 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16277757 | 0.78 | CYP1A2 (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL16282518 | 0.78 | CYP1A2 (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL5837627 | 0.75 | CYP1A2 (0.43) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL5837668 | 0.74 | CYP1A2 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL7521247 | 0.71 | KDM4E (0.41) | ALDH1A1HPGD | |
| SCHEMBL15672061 | 0.70 | CYP1A2 (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19DRD3 | |
| SCHEMBL14563296 | 0.70 | CYP1A2 (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19DRD3 | |
| SCHEMBL5769115 | 0.70 | OPRM1 (0.34) | ALDH1A1CYP2C19RPS6KA2DRD3 | |
| SCHEMBL5768077 | 0.70 | OPRM1 (0.34) | ALDH1A1CYP2C19RPS6KA2DRD3 | |
| SCHEMBL5769113 | 0.70 | OPRM1 (0.34) | ALDH1A1CYP2C19RPS6KA2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | disclosed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPN1, PTPRO, PTPRS | ALDH1A1 1785/4885CYP1A2 2078/4885CYP2C9 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.