Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518346 | 0.91 | ALDH1A1 (0.58) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9090770 | 0.83 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10CNR2 | |
| SCHEMBL3953151 | 0.79 | KDM4E (0.79) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL3103301 | 0.77 | MEN1 (0.81) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL15428037 | 0.77 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL3036074 | 0.76 | KDM4E (0.74) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL9127829 | 0.76 | KDM4E (0.86) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL1345727 | 0.76 | KDM4E (0.73) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL29628842 | 0.75 | KDM4E (0.76) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL29233601 | 0.75 | KDM4E (0.53) | ALDH1A1KDM4EHPGDCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254115-A2 | CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS FOR TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES | Bristol-Myers Squibb Company (US) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001058869-A2 | CANNABINOID RECEPTOR MODULATORS, THEIR PROCESSES OF PREPARATION, AND USE OF CANNABINOID RECEPTOR MODULATORS IN TREATING RESPIRATORY AND NON-RESPIRATORY DISEASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-08-16 | — | — | WO | disclosed |