Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 14/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.48 |
| ▸ | ITGAV | P06756 | 9/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 7/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517076 | 1.00 | ITGB1 (0.48) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7517094 | 0.88 | ITGB3 (0.47) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7516103 | 0.82 | ITGB3 (0.51) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7516114 | 0.82 | ITGB3 (0.51) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7378185 | 0.82 | ITGB3 (0.57) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7378190 | 0.82 | ITGB3 (0.57) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7381188 | 0.81 | ITGB3 (0.51) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7378160 | 0.81 | ITGB3 (0.51) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7377326 | 0.81 | ITGB1 (0.70) | ITGB1ITGB3ITGA2BITGAVITGB5 | |
| SCHEMBL7377320 | 0.81 | ITGB1 (0.70) | ITGB1ITGB3ITGA2BITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891325-B1 | PARA-SUBSTITUTED PHENYLPROPANOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-02-06 | — | — | EP | claimed |