SCHEMBL7517110

SCHEMBL7517110

c1ccc(C(NC(c2ccccn2)c2ccccn2)c2ccccn2)nc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 1/20 0.52
KCNA5 P22460 5/20 0.45
KCNE1 P15382 2/20 0.45
TSHR P16473 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44
SCN8A Q9UQD0 1/20 0.44
KCNH2 Q12809 1/20 0.42
KDM4E B2RXH2 3/20 0.42
LMNA P02545 2/20 0.42
CYP1A2 P05177 2/20 0.42
POLB P06746 1/20 0.42
CCR1 P32246 1/20 0.42
CCR5 P51681 1/20 0.42
CCR8 P51685 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8815913 0.81 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL1062360 0.78 CYP3A4 (0.46) SLC6A2SLC6A4SLC6A3KCNA5TSHR
SCHEMBL5349302 0.76 SLC6A2 (0.48) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL7126294 0.76 SLC6A3 (0.44) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL22321547 0.76 SCN8A (0.49) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL7126297 0.76 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL10210660 0.76 SLC6A2 (0.59) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL3827027 0.76 SLC6A2 (0.58) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL2457219 0.76 SLC6A3 (0.73) SLC6A2SLC6A4SLC6A3KCNA5KCNE1
SCHEMBL2339352 0.74 S1PR2 (0.50) SLC6A2SLC6A4SLC6A3KCNA5KCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020066542-A1 Transition metal complexes with polydentate ligands for enhancing the bleaching and delignifying effect of peroxo compounds DEGUSSA AG (DE) 2002-06-06 US disclosed
EP-1199402-A2 Process for delignifying and/or bleaching fibrous material Degussa AG (DE) 2002-04-24 EP disclosed