SCHEMBL7517176

SCHEMBL7517176

CCCCC(CC(O)Cn1cncn1)c1ccc(Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP19A1 P11511 3/20 0.38
KMT2A Q03164 4/20 0.38
HTT P42858 2/20 0.38
LMNA P02545 1/20 0.38
MEN1 O00255 2/20 0.38
POLB P06746 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
PSEN1 P49768 1/20 0.35
PSEN2 P49810 1/20 0.35
APH1B Q8WW43 1/20 0.35
NCSTN Q92542 1/20 0.35
APH1A Q96BI3 1/20 0.35
PSENEN Q9NZ42 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL9422751 0.87 CYP19A1 (0.42) ALDH1A1CYP3A4CYP19A1KMT2AHTT
SCHEMBL9198943 0.82 KMT2A (0.47) ALDH1A1CYP3A4CYP19A1KMT2AHTT
SCHEMBL10451419 0.77 POLB (0.42) POLBHPGD
SCHEMBL10970720 0.77 CYP19A1 (0.53) ALDH1A1CYP3A4CYP19A1KMT2AHTT
SCHEMBL9480487 0.76 NPSR1 (0.42) ALDH1A1CYP3A4CYP19A1KMT2AMEN1
SCHEMBL9711370 0.74 CYP19A1 (0.47) ALDH1A1CYP3A4CYP19A1KMT2AHTT
SCHEMBL9634892 0.74 CYP19A1 (0.50) ALDH1A1CYP3A4CYP19A1KMT2AHTT
SCHEMBL9480900 0.74 CYP3A4 (0.40) ALDH1A1CYP3A4CYP19A1KMT2ALMNA
Alcohol SCHEMBL27859648 0.74 CYP3A4 (0.39) ALDH1A1CYP3A4CYP19A1KMT2ALMNA
SCHEMBL9285248 0.72 ADA (0.46) POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1257542-A1 METHOD FOR PRODUCING 2-(1,2,4-TRIAZOL-1-YL)-ETHANOLS Bayer Aktiengesellschaft (DE) 2002-11-20 EP disclosed
WO-2001058884-A1 METHOD FOR PRODUCING 2-(1,2,4-TRIAZOL-1-YL)-ETHANOLS BAYER AKTIENGESELLSCHAFT (DE) 2001-08-16 WO disclosed