Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255181 | 0.74 | IDO1 (0.42) | IDO1MAP4K4PARP1ALDH1A1POLB | |
| SCHEMBL5733606 | 0.74 | IDO1 (0.42) | IDO1ALDH1A1POLBRXFP1ADRA2A | |
| SCHEMBL3428780 | 0.70 | IDO1 (0.46) | IDO1GDAPI4KAPI4K2BPI4K2A | |
| SCHEMBL21437991 | 0.68 | HSD17B10 (0.44) | IDO1PARP1ALDH1A1POLBRXFP1 | |
| SCHEMBL14674323 | 0.65 | NUDT1 (0.39) | MAP4K4ALDH1A1KDM4EGAAPI4KA | |
| SCHEMBL1747899 | 0.65 | KDM4A (0.37) | IDO1GDAKDM4EGLAGAA | |
| SCHEMBL87556 | 0.65 | GDA (0.36) | GDATGFBR1KDM4EGLAGAA | |
| Hydrochloric Acid SCHEMBL3353320 | 0.64 | KDM4A (0.36) | IDO1GDAKDM4EPNPPI4KA | |
| Hydrochloric Acid SCHEMBL29616692 | 0.64 | GDA (0.35) | GDAKDM4EPI4KAPI4K2BPI4K2A | |
| Hydrochloric Acid SCHEMBL21683018 | 0.64 | GDA (0.35) | GDAKDM4EPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2912019-A1 | HETEROARYL INHIBITORS OF PDE4 | Tetra Discovery Partners LLC (US) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014066659-A9 | HETEROARYL INHIBITORS OF PDE4 | TETRA DISCOVERY PARTNERS, LLC. (US) | 2015-02-12 | — | — | WO | disclosed |
| WO-2014066659-A1 | HETEROARYL INHIBITORS OF PDE4 | TETRA DISCOVERY PARTNERS, LLC. (US) | 2014-05-01 | — | — | WO | disclosed |
| EP-0643061-B1 | Novel cephalosporin antibiotics and processes for preparation thereof | LUCKY LTD (KR) | 2002-01-30 | — | — | EP | disclosed |
| US-5541175-A | Cephalosporin antibiotics | LUCKY, LTD. (KR) | 1996-07-30 | — | — | US | disclosed |
| EP-0643061-A1 | Novel cephalosporin antibiotics and processes for preparation thereof | LUCKY LTD. (KR) | 1995-03-15 | — | — | EP | disclosed |