Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 13/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191705 | 0.87 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL6600833 | 0.80 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL27487165 | 0.77 | PTGS2 (0.47) | PTGS2PTGS1GRIN1GRIN2B | |
| SCHEMBL6603340 | 0.76 | PTGS2 (0.60) | PTGS2PTGS1GRIN1GRIN2B | |
| SCHEMBL8211725 | 0.73 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL3863130 | 0.72 | PTGS2 (0.87) | PTGS2PTGS1 | |
| SCHEMBL4188728 | 0.72 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL6600013 | 0.71 | PTGS2 (0.85) | PTGS2PTGS1 | |
| SCHEMBL4196932 | 0.71 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL4190200 | 0.70 | PTGS2 (0.77) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | BLACK LAWRENCE A (US) | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013318-A1 | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | PTGS1, PTGIS, PTGS2 | PTGS2 3/4885PTGS1 1/4885GRIN1 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.