Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358984 | 0.84 | LMNA (0.53) | LMNATHRB | |
| SCHEMBL31633561 | 0.81 | LMNA (0.50) | LMNATHRB | |
| SCHEMBL14615983 | 0.79 | LMNA (0.47) | LMNATHRB | |
| SCHEMBL16356371 | 0.79 | LMNA (0.47) | LMNATHRB | |
| SCHEMBL28948866 | 0.79 | LMNA (0.47) | LMNATHRB | |
| SCHEMBL7730742 | 0.77 | LMNA (0.60) | LMNATHRB | |
| SCHEMBL8588637 | 0.77 | LMNA (0.45) | LMNATHRB | |
| SCHEMBL8589179 | 0.77 | LMNA (0.45) | LMNATHRB | |
| SCHEMBL22534482 | 0.74 | LMNA (0.43) | LMNATHRB | |
| SCHEMBL20464017 | 0.74 | LMNA (0.43) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799420-B1 | METHOD FOR SYNTHESIZING 2,7-DIMETHYL-2,4,6-OCTATRIENE-1,8-DIALDEHYDE | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2016-11-16 | — | — | EP | claimed |
| US-9187394-B2 | Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-11-17 | — | — | US | claimed |
| US-20140378711-A1 | METHOD FOR SYNTHESIZING 2,7-DIMETHYL-2,4,6-OCTATRIENE-1,8-DIALDEHYDE | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2014-12-25 | — | — | US | claimed |
| EP-2799420-A1 | METHOD FOR SYNTHESIZING 2,7-DIMETHYL-2,4,6-OCTATRIENE-1,8-DIALDEHYDE | Nanjing University Of Technology (CN) | 2014-11-05 | — | — | EP | claimed |
| CN-103172504-B | Synthesis method of 2, 7-dimethyl-2, 4, 6-octatriene-1, 8-dialdehyde | NANJING TECH UNIVERSITY (CN) | 2014-10-08 | — | — | CN | claimed |
| CN-103172504-A | Synthesis method of 2, 7-dimethyl-2, 4, 6-octatriene-1, 8-dialdehyde | NANJING UNIVERSITY OF TECHNOLOGY | 2013-06-26 | — | — | CN | claimed |
| US-10023589-B2 | Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators | HOFFMANN-LA ROCHE INC. (US) | 2018-07-17 | — | — | US | disclosed |
| EP-2799420-B1 | METHOD FOR SYNTHESIZING 2,7-DIMETHYL-2,4,6-OCTATRIENE-1,8-DIALDEHYDE | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2016-11-16 | — | — | EP | disclosed |
| US-20160207936-A1 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | HOFFMANN-LA ROCHE INC. | 2016-07-21 | — | — | US | disclosed |
| US-9255110-B2 | Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators | ROCHE PALO ALTO LLC (US) | 2016-02-09 | — | — | US | disclosed |
| US-9187394-B2 | Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-11-17 | — | — | US | disclosed |
| US-9187394-B2 | Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-11-17 | — | — | US | disclosed |
| US-9187394-B2 | Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2015-11-17 | — | — | US | disclosed |
| US-5929288-A | A POLYENE O,O-DIALKYL ACETAL OR POLYENE DI(O,O-DIALKYL ACETAL) IS REACTED WITH A 1-ALKOXY-1,3-DIENE IN THE PRESENCE OF A LEWIS ACID OR A BRONSTED ACID. THE REACTION MIXTURE IS THEN HYDROLYZED AND THE ALCOHOL IS CLEAVED UNDER BASIC CONDITIONS. | ROCHE VITAMINS INC. (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0919547-A1 | Preparation of polyenaldehydes | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-02 | — | — | EP | disclosed |
| US-5786518-A | HALOHYDROXYLATION OF ALKOXY-2-METHYL-1,3-BUTADIENE WITH ALKANOL AND HALOGEN THEN HYDROLYSIS | ROCHE VITAMINS INC. (US) | 1998-07-28 | — | — | US | disclosed |
| CN-1178783-A | Preparation method of gamma-tiglic aldehyde | HOFFMANN LA ROCHE (CH) | 1998-04-15 | — | — | CN | disclosed |
| EP-0825168-A2 | Preparation of gamma-halotiglinaldehydes | F. HOFFMANN-LA ROCHE AG (CH) | 1998-02-25 | — | — | EP | disclosed |
| CN-1170708-A | Manufacture of polyene (Di) aldehydes | HOFFMANN LA ROCHE (CH) | 1998-01-21 | — | — | CN | disclosed |
| EP-0816334-A1 | Preparation of polyenic (di)aldehydes | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207936-A1 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | IRAK4, IRAK1, IRAK2 | LMNA 2020/4885THRB 712/4885 |
| US-10023589-B2 | Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators | IRAK4, IRAK1, IRAK2 | LMNA 2020/4885THRB 712/4885 |
| US-20140378711-A1 | METHOD FOR SYNTHESIZING 2,7-DIMETHYL-2,4,6-OCTATRIENE-1,8-DIALDEHYDE | TMT1A, DIMT1, TET1 | LMNA 3731/4885THRB 2730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.