Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14615983 | 0.87 | LMNA (0.47) | LMNATHRB | |
| SCHEMBL16356371 | 0.87 | LMNA (0.47) | LMNATHRB | |
| SCHEMBL7517448 | 0.84 | LMNA (0.45) | LMNATHRB | |
| SCHEMBL7649563 | 0.82 | LMNA (0.43) | LMNATHRB | |
| SCHEMBL22534482 | 0.82 | LMNA (0.43) | LMNATHRB | |
| SCHEMBL1568155 | 0.81 | THRB (0.57) | LMNATHRBL3MBTL1 | |
| SCHEMBL4094836 | 0.79 | LMNA (0.53) | LMNATHRBL3MBTL1 | |
| SCHEMBL8589179 | 0.78 | LMNA (0.45) | LMNATHRB | |
| SCHEMBL8588637 | 0.78 | LMNA (0.45) | LMNATHRB | |
| SCHEMBL31633561 | 0.76 | LMNA (0.50) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423366-B | Preparation method of pirfenidone | 山东汇海医药化工有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-111423366-A | Preparation method of pirfenidone | 山东汇海医药化工有限公司 | 2020-07-17 | — | — | CN | claimed |
| US-7553863-B2 | Ultrapure 4-methylpyrazole | Paladin Labs (Barbados) Inc. (BB) | 2009-06-30 | — | — | US | claimed |
| EP-1948613-A2 | PROCESS FOT THE PREPARATION OF ULTRAPURE 4-METHYLPYRAZOLE | Orphan Medical Inc. (US) | 2008-07-30 | — | — | EP | claimed |
| CN-101163679-A | Process for preparing ultrapure 4-methylpyrazole | ORPHAN MEDICAL INC (US) | 2008-04-16 | — | — | CN | claimed |
| US-20070244330-A1 | solution containing 4-methyl pyrazole containing less than 0.1% pyrazole, less than 10 ppm each of hydrazine and nitrobenzaldehyde; reacting propionaldehyde with triethyl orthoformate; reacting final intermediate with hydrazine to produce to produce 4-methylpyrazole; antidote for ethylene glycol posion | ENDO OPERATIONS LIMITED (IE) | 2007-10-18 | — | — | US | claimed |
| WO-2006115626-A2 | PROCESS FOR THE PREPARATION OF ULTRAPURE 4-METHYLPRAZOLE | ORPHAN MEDICAL, INC. (US) | 2006-11-02 | — | — | WO | claimed |
| JP-10072554-A | — | — | None | — | — | JP | disclosed |
| EP-4683921-A1 | INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-01-28 | — | — | EP | disclosed |
| US-12351584-B2 | Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-07-08 | — | — | US | disclosed |
| WO-2025079634-A1 | CONDENSED RING COMPOUND, AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2025-04-17 | — | — | WO | disclosed |
| WO-2024193542-A1 | INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-09-26 | — | — | WO | disclosed |
| US-20230286993-A1 | CYCLIC ETHER DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYAMIDE | BOEHRINGER INGELHEIM INT (DE) | 2023-09-14 | — | — | US | disclosed |
| JP-H1072554-A | CYANINE COLORANT | FUJI PHOTO FILM CO LTD | 1998-03-17 | — | — | JP | disclosed |
| US-5387502-A | Containing specified cyanine dye sensitizer; high sensitivity, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| US-4410733-A | Preparation of acetals of malonaldehyde | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-18 | — | — | US | disclosed |
| US-4283475-A | Pentamethine thiopyrylium salts, process for production thereof, and photoconductive compositions containing said salts | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |
| US-4104273-A | Derivatives of 3-cyano-pyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4075209-A | Process for preparing substituted 2,4-diaminopyrimidines and isoxazole intermediate | HOFFMANN-LA ROCHE, INC. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4028084-A | Derivatives of 3-carboxy pyrid-2-ones | ROHM AND HAAS COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244330-A1 | solution containing 4-methyl pyrazole containing less than 0.1% pyrazole, less than 10 ppm each of hydrazine and nitrobenzaldehyde; reacting propionaldehyde with triethyl orthoformate; reacting final intermediate with hydrazine to produce to produce 4-methylpyrazole; antidote for ethylene glycol posion | CYP3A43, CYP3A5, CYP3A4 | LMNA 3717/4885THRB 2287/4885L3MBTL1 4068/4885 |
| US-20230286993-A1 | CYCLIC ETHER DERIVATIVES OF PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXYAMIDE | CNP, PDE3A, PDE5A | LMNA 2620/4885THRB 3243/4885L3MBTL1 4533/4885 |
| US-12351584-B2 | Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide | CNP, PDE3A, PDE5A | LMNA 2620/4885THRB 3243/4885L3MBTL1 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.