Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 10/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CD69 | Q07108 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526340 | 0.88 | DDB1 (0.44) | KDM4EALDH1A1HPGDTDP1POLB | |
| SCHEMBL8460607 | 0.83 | PTPN1 (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL7525144 | 0.79 | PTGDR2 (0.40) | KDM4EALDH1A1HPGDTDP1POLB | |
| SCHEMBL7962737 | 0.78 | ABCB1 (0.39) | KDM4EPOLBACHE | |
| SCHEMBL8099246 | 0.77 | ACHE (0.45) | KDM4EALDH1A1HPGDTDP1POLB | |
| SCHEMBL7822661 | 0.77 | AKR1B1 (0.40) | KDM4ETDP1ACHE | |
| SCHEMBL7976448 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1POLBSMN1; SMN2ACHE | |
| SCHEMBL9094161 | 0.76 | TOP1 (0.51) | ALDH1A1POLBSMN1; SMN2ACHEHSD17B10 | |
| SCHEMBL7522357 | 0.76 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDTDP1L3MBTL1 | |
| SCHEMBL7962739 | 0.76 | ACHE (0.37) | KDM4EPOLBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417213-B2 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-09 | — | — | US | disclosed |
| US-20020006944-A1 | Tricyclic compounds, their production and use | OHKAWA SHIGENORI (JP) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006944-A1 | Tricyclic compounds, their production and use | CNR1, PTGER1, PTGDR | KDM4E 4000/4885ALDH1A1 1662/4885HPGD 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.