Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748698 | 1.00 | ADORA3 (0.61) | ADORA3GAAMEN1POLBKMT2A | |
| SCHEMBL7507051 | 0.81 | POLB (0.51) | ADORA3POLB | |
| SCHEMBL9650033 | 0.79 | ADORA3 (0.58) | ADORA3GAAMEN1KMT2AGABRA2 | |
| SCHEMBL11402491 | 0.78 | ADORA3 (0.60) | ADORA3GAAMEN1POLBKMT2A | |
| SCHEMBL10730143 | 0.77 | KDM4E (0.50) | ADORA3GAAMEN1KMT2AGABRA2 | |
| SCHEMBL7269351 | 0.76 | POLB (0.55) | ADORA3MEN1POLBKMT2A | |
| SCHEMBL8817316 | 0.76 | ADORA3 (0.42) | ADORA3GAAGABRA2GABRB2GABRP | |
| SCHEMBL8034425 | 0.76 | ADORA3 (0.61) | ADORA3MEN1POLBKMT2ASPR | |
| SCHEMBL28887969 | 0.76 | ADORA1 (0.49) | ADORA3POLB | |
| SCHEMBL11399240 | 0.75 | GAA (0.48) | ADORA3GAAGABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743945-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 2002-03-06 | — | — | EP | disclosed |
| US-5741785-A | IMIDAZOLO(1,2-A)QUINOXALINONE COMPOUNDS; ANTIISCHEMIC AGENTS; NERVOUS SYSTEM DISORDERS | NOVO NORDISK A/S (DK) | 1998-04-21 | — | — | US | disclosed |
| EP-0743945-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021842-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-08-17 | — | — | WO | disclosed |
| US-4644002-A | Imidazo[2,1-C]quinolines, useful as antiallergic agents | ROUSSEL UCLAF (FR) | 1987-02-17 | — | — | US | disclosed |
| US-4474784-A | ANTIALLERGENS | ROUSSEL UCLAF (FR) | 1984-10-02 | — | — | US | disclosed |
| US-4333934-A | ANTIALLERGIC ACTIVITY | ROUSSEL UCLAF (FR) | 1982-06-08 | — | — | US | disclosed |
| US-4291033-A | ANTIALLERGENS | ROUSSEL UCLAF (FR) | 1981-09-22 | — | — | US | disclosed |
| US-4254123-A | FOR TREATMENT OF ASTHMA; ANTIALLERGENS | ROUSSEL UCLAF (FR) | 1981-03-03 | — | — | US | disclosed |