Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | PDE8A | O60658 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | PDE9A | O76083 | 1/20 | 0.45 |
| ▸ | PDE8B | O95263 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266972 | 0.82 | POLB (0.47) | POLBPARP1ADORA3KDM4EALDH1A1 | |
| SCHEMBL9255705 | 0.80 | ADORA1 (0.51) | POLBPARP1ADORA3KDM4EALDH1A1 | |
| SCHEMBL9256388 | 0.79 | ADORA3 (0.55) | POLBPARP1ADORA3KDM4EALDH1A1 | |
| SCHEMBL7507051 | 0.78 | POLB (0.51) | POLBPARP1ADORA3KDM4EALDH1A1 | |
| SCHEMBL9262896 | 0.77 | ADORA3 (0.49) | POLBPARP1ADORA3KDM4EALDH1A1 | |
| SCHEMBL30748698 | 0.76 | ADORA3 (0.61) | POLBADORA3MEN1KMT2A | |
| SCHEMBL7517896 | 0.76 | ADORA3 (0.61) | POLBADORA3MEN1KMT2A | |
| SCHEMBL9043231 | 0.75 | POLB (0.48) | POLBPARP1ADORA3KDM4EALDH1A1 | |
| SCHEMBL9259533 | 0.75 | MAP4K4 (0.59) | POLBPARP1ADORA3KDM4EALDH1A1 | |
| SCHEMBL9265209 | 0.75 | POLB (0.48) | POLBPARP1ADORA3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400583-B1 | Imidazoquinoxalinones, their aza analogs and process for their preparation | BERLEX LAB (US) | 1999-11-17 | — | — | EP | claimed |
| US-5055465-A | IMIDAZOQUINOXALINONES, THEIR AZA ANALOGS AND PROCESS FOR THEIR PREPARATION | BERLEX LABORATORIES, INC. (US) | 1991-10-08 | — | — | US | claimed |
| EP-0400583-A1 | Imidazoquinoxalinones, their aza analogs and process for their preparation | BERLEX LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | claimed |