Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801531 | 0.79 | HPGD (0.69) | ALDH1A1POLBKMT2AHPGDMAPK1 | |
| SCHEMBL1783438 | 0.74 | ALDH1A1 (0.54) | ALDH1A1POLBKMT2AHPGDMAPK1 | |
| SCHEMBL3023400 | 0.73 | HPGD (0.63) | ALDH1A1POLBKMT2AHPGDMAPK1 | |
| SCHEMBL5621143 | 0.71 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AHPGDMAPK1 | |
| SCHEMBL7562987 | 0.70 | AR (0.42) | ALDH1A1POLBKMT2AHPGDHTT | |
| SCHEMBL20568724 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KMT2AHPGDHTTSMN1; SMN2 | |
| SCHEMBL27942077 | 0.70 | ALDH1A1 (0.76) | ALDH1A1POLBKMT2AHPGDMAPK1 | |
| SCHEMBL11829885 | 0.70 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AHPGDMAPK1 | |
| SCHEMBL11652356 | 0.70 | CYP1A2 (0.80) | ALDH1A1POLBKMT2AHPGDMAPK1 | |
| SCHEMBL69310 | 0.70 | HPGD (1.00) | ALDH1A1POLBKMT2AHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |