Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | TCF4 | P15884 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765737 | 1.00 | LMNA (0.46) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL4674509 | 0.87 | LMNA (0.51) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL29117303 | 0.80 | GRM2 (0.61) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL4672907 | 0.79 | L3MBTL1 (0.51) | LMNAMAPTKLKB1HSD17B10RAB9A | |
| SCHEMBL949903 | 0.77 | HSD17B10 (0.61) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL4676350 | 0.77 | KLKB1 (0.49) | ALDH1A1SMN1; SMN2KLKB1HSD17B10RAB9A | |
| SCHEMBL4677429 | 0.76 | HSD17B10 (0.48) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL4672069 | 0.76 | LMNA (0.43) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL752774 | 0.76 | LMNA (0.61) | LMNAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL4673827 | 0.76 | HSD17B10 (0.47) | LMNAMAPTALDH1A1KLKB1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |