Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509973 | 0.83 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2RAB9ALMNAHPGD | |
| SCHEMBL1330352 | 0.83 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2RAB9ALMNAHPGD | |
| SCHEMBL9386894 | 0.83 | HSD17B10 (0.50) | HSD17B10SMN1; SMN2RAB9ALMNAHPGD | |
| SCHEMBL29985720 | 0.79 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2RAB9ALMNAHPGD | |
| SCHEMBL6219872 | 0.78 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2RAB9ALMNACYP2C19 | |
| SCHEMBL85536 | 0.78 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2RAB9ALMNACYP2C19 | |
| SCHEMBL67044 | 0.78 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2RAB9ALMNACYP2C19 | |
| SCHEMBL67045 | 0.78 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2RAB9ALMNACYP2C19 | |
| SCHEMBL27877016 | 0.78 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2RAB9ALMNACYP2C19 | |
| SCHEMBL14913989 | 0.76 | HSD17B10 (0.43) | HSD17B10SMN1; SMN2HPGDEPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001079177-A1 | CYCLIC DIAZA COMPOUNDS FOR TREATING NEURODEGENERATIVE DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |